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5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

A genetic change in the EDAR gene causes the unique hair traits found in East Asians.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

No treatment fully prevents hair loss from chemotherapy yet.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Improving skin barrier and using antifungal treatments can help manage dandruff.

Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.

Researchers identified genes linked to coat color, body size, cashmere production, and high altitude adaptation in goats.

Turing patterns are now recognized as important in developmental biology.

All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.

Prolactin affects hair growth cycles and can cause early hair follicle regression.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.

The EDAR gene greatly affects hair thickness in Asian populations.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

Minoxidil and finasteride effectively treat hair loss.

Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.

Cancer patients treated with immune checkpoint inhibitors may develop alopecia, but some hair regrowth is possible with treatment.

FOXO1 is important for wound healing, but its dysfunction in diabetes can slow the healing process.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.