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360-390 / 1000+ resultsresearch OsCSLD1 Mediates NH4+-Dependent Root Hair Growth Suppression and AMT1;2 Expression in Rice (Oryza sativa L.)
This study suggests that CSLD1 is key to nitrogen-dependent root hair elongation and regulation of AMT1;2 expression in rice roots.
research Bi-allelic Mutations in LSS, Encoding Lanosterol Synthase, Cause Autosomal-Recessive Hypotrichosis Simplex
This study identified five mutations in the gene LSS in individuals with unexplained hypotrichosis simplex, highlighting a potential role of mislocalized LSS proteins in disrupting hair follicle biology.
research 689 Efficacy of CD101, a novel echinocandin, in the treatment of dermatophytosis using a Guinea Pig (GP) Model
In a guinea pig model of dermatophytosis, this study found that subcutaneous CD101, dosed once weekly, demonstrated significant clinical and mycological efficacy compared to the vehicle control and the oral antifungal terbinafine, suggesting potential for CD101 in treating fungal skin infections.
research Visible-to-Near IR Quantum Dot–Based Hypermulticolor High-Content Screening of Herbal Medicines for the Efficacy Monitoring of Hair Growth Promotion and Hair Loss Inhibition
This study observed that certain herbal extracts may promote hair growth and inhibit hair loss in cell lines by affecting specific protein expressions similarly to minoxidil.
research The growth of human scalp hair in females using visible red light laser and LED sources
This study found that low-level laser therapy significantly increased hair growth in women with androgenic alopecia, achieving a 37% greater increase in hair counts compared to placebo.
research DataSheet1_BBS7–SHH Signaling Activity Regulates Primary Cilia for Periodontal Homeostasis.csv
This study found that downregulation of BBS7 in periodontal ligament cells was associated with reduced Sonic hedgehog signaling, which plays a crucial role in maintaining PDL homeostasis.
research Corneal Endothelial Cell Fate Is Maintained by LGR5 Through the Regulation of Hedgehog and Wnt Pathway
This study found that LGR5 is uniquely expressed in human corneal endothelial cells and maintains endothelial cell phenotypes while inhibiting mesenchymal transformation through the Wnt pathway.
research A case report of Graham-Little–Piccardi–Lassueur syndrome
This report describes a rare case of Graham-Little–Piccardi–Lassueur syndrome in a 46-year-old male, highlighting its typical features such as scarring alopecia and lichenoid follicular eruptions.
research Functional analysis of the PIP5K1A gene in Liaoning Cashmere goats: an investigation based on bioinformatics, tissue localization, and biological functions
This study found that in Liaoning cashmere goats, overexpression of the PIP5K1A gene enhances skin fibroblast proliferation, while interference with this gene reverses melatonin-induced proliferation, and PIP5K1A regulates certain miRNA expressions, suggesting a role in improving cashmere yield and quality.
research P085 Therapeutic effects of growth factor cocktail including FGF9 scalp application in patients with androgenetic alopecia
This study found that growth factor cocktail treatment including FGF9, combined with microneedling, significantly improved hair density in androgenetic alopecia patients compared to treatment with regular GFC or normal saline.
research A Novel, Hand-Held, and Low-Level Light Therapy Device for the Treatment of Acne Vulgaris: A Single-Arm, Prospective Clinical Study
This study evaluated a novel hand-held low-level light therapy device for treating mild-to-moderate acne, finding it significantly reduced inflammatory lesions and moderate acne severity without severe adverse reactions, while also reducing Cutibacterium acnes viability in vitro.
research Minoxidil niosome loaded dissolving microneedle delivery system for treatment of DHT induced androgenic alopecia in C57BL/6 Mice
research On rational series in one variable over certain dioids
This study found that oral administration of Lactococcus lactis subsp. cremoris H61 to aged mice was associated with reduced bone loss, fewer skin ulcers, and less hair loss compared with controls.
research A new label-free screen for steroid 5α-reductase inhibitors using LC-MS
This study developed and validated a label-free assay using LC-MS to screen for S5αR inhibitors, identifying Thai herbal extracts, Impatiens balsamina L. and Curcuma longa L., as promising sources.
research Analysis of lncRNAs Expression Profiles in Hair Follicle of Hu Sheep Lambskin
This study identified differentially expressed mRNAs and lncRNAs in Hu sheep hair follicles, suggesting certain genes and pathways are involved in the development of wool curvature patterns.
research Evaluation of the palatal wound healing effect of wound dressing carrying GSK-3 antagonist tideglusib on rats
This study found that tideglusib delivered topically in a bacterial cellulose hydrogel showed positive effects on the wound healing of rat palatal mucosa, as observed through macroscopic, histomorphometric, and immunohistochemical evaluations.
research Compound glycyrrhizin promotes hair growth in C57BL/6 mice by regulating the Wnt/β-catenin pathway
In this study, compound glycyrrhizin promoted hair regrowth in a testosterone-induced alopecia mouse model and increased human hair dermal papilla cell proliferation, likely through activating the Wnt/β-catenin pathway.
research Distinct expression profile of stem cell markers, LGR5 and LGR6, in basaloid skin tumors
This study documented distinct expression patterns of stem cell markers LGR5 and LGR6 in various human skin tumors, highlighting differences in their potential roles and contributions to tumor development.
research Low-level laser treatment stimulates hair growth via upregulating Wnt10b and β-catenin expression in C3H/HeJ mice
This study found that low-level laser treatment may promote hair regrowth in mice by activating the Wnt10b/ß-catenin pathway and inducing the anagen phase of hair follicles.
research Anti-Oxidant and Hair-Growth-Promoting Effect of Pectin Lyase-Modified Red Ginseng Extract (GS-E3D)
This study found that pectin lyase-modified red ginseng extract may promote hair growth by enhancing antioxidant and anti-inflammatory activities, along with inhibiting testosterone-induced 5-alpha-reductase in human hair dermal papilla cells.
research Anti-androgenic activities of Ganoderma lucidum
In this study, Ganoderma lucidum extract was found to significantly inhibit 5alpha-reductase activity and testosterone-induced prostate growth in rats, suggesting potential use for treating benign prostatic hyperplasia.
research The Science of Light Biostimulation and Low Level Laser Therapy (LLLT)
This article introduces a series on low level laser light therapy, focusing on its science, regulatory aspects, and controlled trial methodologies, but reports no new clinical results.
research The metabolites of Bifidobacterium longum BB536 alleviate DHT-damaged human dermal papilla cells by activating WNT/β-catenin signaling
This study reported that in laboratory conditions, a cell-free supernatant of Bifidobacterium longum BB536 promoted human dermal papilla cell proliferation and reduced damage and apoptosis caused by dihydrotestosterone, suggesting potential use as a preventative treatment for androgenic alopecia by modulating specific signaling pathways.
research Lambertianic Acid from Platycladus orientalis Inhibits Muscle Atrophy in Dexamethasone-Induced C2C12 Muscle Atrophy Cells
This study found that lambertianic acid from Platycladus orientalis leaves may protect against dexamethasone-induced skeletal muscle atrophy by reducing atrophy-related proteins without affecting cell viability.
research Efficacy and tolerability of HDMHG0401-10 in Patients with Androgenetic Alopecia: A Randomized Double-blind Placebo-controlled Trial
This study reported that the topical treatment HDMHG0401-10 significantly improved hair density in men with androgenetic alopecia compared to placebo, although subjective hair growth ratings were not significantly different.
research The 532 Nm Laser Treatment Promotes the Proliferation of Tendon- Derived Stem Cells and Up-Regulates Nr4a1 to Stimulate Tenogenic Differentiation
This study found that a 532 nm laser at 15 J/cm² enhanced the proliferation and differentiation of tendon-derived stem cells in rats, potentially accelerating tendon healing through the up-regulation of Nr4a1.
research Low‐Level Light Therapy Downregulates Scalp Inflammatory Biomarkers in Men With Androgenetic Alopecia and Boosts Minoxidil 2% to Bring a Sustainable Hair Regrowth Activity
This study observed that adding low-level light therapy with the GentleWaves® device to Minoxidil significantly boosted hair regrowth in men with androgenetic alopecia by reducing scalp inflammation.
research Qualidade de vida relacionada à saúde em homens e mulheres com alopecia androgenética em uso de terapia com luz de baixa intensidade
This study found that low-intensity light therapy improved quality of life related to emotional, psychosocial, and symptom domains in individuals with androgenic alopecia, with a greater impact observed in women.
research De novo assembly and annotation of Asiatic lion (Panthera leo persica) genome
This study provides the first draft of the male Asiatic lion's whole genome, revealing low genomic diversity and highlighting conservation concerns.