A Novel Hand-Held Low-Level Light Therapy Device for the Treatment of Acne Vulgaris: A Single-Arm Prospective Clinical Study

    January 2023 in “ Dermatologic Therapy ”
    Euy Hyun Chung, Ji Won Son, Yun Su Eun, Na Gyeong Yang, Jae yoon Kim, Sulhee Lee, Nam Hun Heo, Jinhui Rhee, Sung Yul Lee, Yongsung Hwang, Jung Eun Kim
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    TLDR A new hand-held light therapy device was found to be safe and effective for treating mild-to-moderate acne.
    A prospective clinical study involving 57 patients with mild-to-moderate acne found that a novel hand-held low-level light therapy device was safe and effective in treating acne. The device, which uses a 680 nm red laser diode and a 450 nm blue light-emitting diode, was self-administered by patients at home daily for 4 weeks. Results showed a significant decrease in the mean number of inflammatory acne lesions at weeks 4 and 8, with reductions of 64.7% and 59.3% in the per-protocol and intention-to-treat groups respectively. No severe adverse reactions were reported. The study also found a significant reduction in the viability of Cutibacterium acnes, a causative agent of acne vulgaris, following low-level light therapy exposure in vitro. However, the study noted that further large-scale studies are needed to confirm these findings.
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