May 2023 in “Research Square (Research Square)” In this study, researchers observed that treatment with Agaricus subrufescens ethanolic extract improved blood glucose, testosterone levels, and menstrual irregularity in rat models of letrozole-induced Polycystic Ovarian Syndrome, also noting a decrease in elevated liver and ovary weights, suggesting protective effects on renal function.
2 citations
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March 2021 in “Dermatologic Therapy” This study found that low-level laser therapy significantly increased hair counts in women with female pattern hair loss but not in those with telogen effluvium, without serious adverse events.
1 citations
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November 2023 in “Journal of ovarian research” In this study involving rats with letrozole-induced polycystic ovary syndrome, Agaricus subrufescens significantly reduced blood glucose, total cholesterol, testosterone levels, and renal markers, suggesting its potential protective effects on both metabolic and reproductive parameters.
September 2023 in “Medicina Estética Revista Científica de la Sociedad Española de Medicina Estética (SEME)” This research reported that the FDA approved Litfulo® (ritlecitinib) as the first oral treatment for severe alopecia areata in adolescents over 12 years old, with 23% of treated patients showing significant hair regrowth in clinical trials compared to 1.6% with placebo.
158 citations
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June 2014 in “Journal of Lipid Research” This review summarizes recent discoveries of GPCRs for lysophosphatidylserine and lysophosphatidylinositol, detailing their roles as lipid mediators, but reports no new experimental results.
22 citations
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August 2020 in “Journal of the American Academy of Dermatology” Women with lichen planopilaris and frontal fibrosing alopecia often have other health issues like hypothyroidism and lupus.
3 citations
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September 2022 in “European Journal of Dermatology” This report identifies a novel splice-site variant in the LAMB3 gene linked to junctional epidermolysis bullosa, emphasizing the need for gene sequencing in diagnosing the disease.
2 citations
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July 2019 in “Indian dermatology online journal” This report documents a rare case of familial eyelash trichomegaly and synophrys in three siblings, with one sister also having loose anagen hair syndrome, an unreported association.
20 citations
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November 2020 in “Stem Cell Research & Therapy” This study found that placenta-derived mesenchymal stem cells overexpressing PRL-1 inhibited adipogenesis in orbital fibroblasts from Graves’ ophthalmopathy patients by modulating specific signaling pathways, suggesting a potential therapeutic strategy.
16 citations
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April 2016 in “Medicine” This study described a case where lupus erythematosus panniculitis preceded the diagnosis of systemic lupus erythematosus, highlighting the need for regular follow-ups in LEP patients for potential SLE development.
3 citations
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August 2024 in “Molecular Biology Reports” This study found that the lncRNA018392, responsive to melatonin, accelerates cell proliferation in cashmere goats by recruiting the transcription factor SPI1 to upregulate the nearby gene CSF1R, which may explain the molecular mechanisms of cashmere growth.
6 citations
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September 2018 in “International Journal of Molecular Sciences” This study found that intramuscular injections of a PRP-derivative in healthy beagle dogs did not result in statistically significant changes in lumbar muscle tissue or IGF-1 blood concentration, suggesting the treatment may be safe at therapeutic doses.
1 citations
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January 2019 in “Journal of Nuclear Technologyin Applied Science (JNTAS) (Print)” This study found that low-level laser therapy accelerates skin regeneration in gamma-irradiated mice and enhances the biostimulatory effect on hair follicles.
106 citations
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April 2013 in “Dermatologic Surgery” This study found that low-level light therapy significantly increased hair density and diameter in androgenetic alopecia patients compared to a sham device, suggesting it could be an effective treatment option.
In this clinical case study, a 30-year-old man with systemic lupus erythematosus was diagnosed with both catastrophic antiphospholipid syndrome and acquired haemophilia A, successfully treated with immunosuppressive therapy, plasma exchange, and IVIG, leading to a favourable outcome.
1 citations
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October 2023 in “European Journal of Dermatology” This study found that combining hair transplantation with platelet-rich plasma led to significantly better outcomes, such as reduced hair loss area and increased hair regeneration, compared to hair transplantation alone in patients with androgenic alopecia.
81 citations
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August 2014 in “Lasers in Surgery and Medicine” This study found that low-level laser therapy significantly increased hair growth in women with androgenic alopecia, achieving a 37% greater increase in hair counts compared to placebo.
January 2017 in “Open Journal of Endocrine and Metabolic Diseases” This case report identifies an adolescent with symptoms indicative of Dunnigan-type partial lipodystrophy, emphasizing the need for early diagnosis to manage associated metabolic complications and improve self-esteem.
3 citations
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February 2024 in “Journal of the American Academy of Dermatology” This source discusses that while oral JAK inhibitors are used for treating lichen planopilaris and frontal fibrosing alopecia, they carry significant risk of adverse events; two cases showed promising results using tofacitinib cream as a safer topical alternative.
This case study reports the first known instance of lichen planopilaris being associated with multiple autoimmune syndrome in a woman with hypothyroidism and Crohn's disease.
2 citations
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November 2023 in “Skin Appendage Disorders” This case report documents the rare occurrence of lipedematous scalp in two black Caribbean female siblings, suggesting a potential genetic factor and noting psychiatric co-morbidities as novel associations.
1 citations
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August 2019 in “Chinese Medical Journal” This case report describes a 43-year-old man who developed lupus miliaris disseminatus faciei after discontinuation of cyclosporine A post-stem cell transplantation, successfully treated with oral isotretinoin and topical tacrolimus.
51 citations
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May 2004 in “American journal of ophthalmology” This study reports that poliosis can be an adverse effect of topical prostaglandin F2α analog therapy in patients treated for primary open angle glaucoma.
February 2022 in “Research Square (Research Square)” In this study, researchers successfully expressed recombinant human FGF5 protein in Arabidopsis, finding that this protein inhibits hair regeneration both in vitro and in vivo.
1 citations
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December 2012 in “Journal of dermatological science” This study introduces ficlatuzumab, an anti-HGF monoclonal antibody, in combination with gefitinib in a phase 2 trial to address EGFR TKI resistance in Asian NSCLC patients.
November 2012 in “Annales de Dermatologie et de Vénéréologie” This report describes the first known pediatric cases of frontal fibrosing alopecia, a condition typically affecting postmenopausal women, highlighting its occurrence in children including female twins.
September 2017 in “Journal of Investigative Dermatology” LRIG1 protein affects hair growth by regulating skin receptors, leading to hair loss when overexpressed.
January 2010 in “Chinese Medical Journal of Metallurgical Industry” This study found that leflunomide combined with prednisone showed good efficacy and tolerance in treating lupus nephritis where cyclophosphamide was ineffective or intolerable.
June 2023 in “British journal of dermatology/British journal of dermatology, Supplement” This study reports a rare case of two siblings with lipoedematous scalp, suggesting a possible genetic link that warrants further investigation.
15 citations
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June 2021 in “Medicina” This study found that combined intense pulsed light and low-level light therapy significantly improved ocular surface outcomes and quality of life for patients with meibomian gland dysfunction and dry eye disease.