January 2026 in “SKIN The Journal of Cutaneous Medicine” Rituximab treatment led to complete hair regrowth and improved skin in a woman with pemphigus foliaceus.
Media coverage led to more dermatologists prescribing low-dose oral minoxidil for hair loss.
June 2018 in “Surgical Case Reports” S-1 treatment led to a complete response in pancreatic cancer with manageable side effects.
March 2014 in “Journal of The American Academy of Dermatology” Azathioprine treatment led to rapid hair regrowth in a woman with alopecia universalis.
184 citations
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February 2015 in “EBioMedicine” This study observed that baricitinib treatment led to significant improvement in a patient's alopecia areata symptoms and suggests further clinical trials to explore its potential as a treatment.
130 citations
,
February 2018 in “Journal of Investigative Dermatology” This study found that tofacitinib led to ≥50% hair regrowth in eight out of twelve patients with moderate to severe alopecia areata, suggesting a potential benefit for using JAK inhibitors in treating this condition.
63 citations
,
April 1985 in “Journal of the American Academy of Dermatology” This study observed that topical PUVA treatment led to excellent or good hair regrowth in 45.4% of patients with alopecia areata, though many experienced relapse after treatment stopped.
54 citations
,
September 2013 in “Fertility and Sterility” This study found that discontinuing finasteride led to a significant increase in sperm counts for most men with reduced fertility, though hormone levels and other semen parameters remained unchanged.
45 citations
,
July 2008 in “International Journal of Dermatology” This study found that oral sulfasalazine led to varying hair regrowth outcomes in patients with persistent alopecia areata, with 56.3% showing moderate to good responses.
41 citations
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November 1993 in “Journal of The American Academy of Dermatology” This study found that DPCP treatment led to cosmetically acceptable hair regrowth in 38% of patients with chronic severe alopecia areata, while adding 5% minoxidil showed no significant clinical benefit.
34 citations
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June 1990 in “British Journal of Dermatology” This study found that etretinate treatment led to an increase in plucked telogen hair counts, suggesting a reduction in the duration of anagen as the primary cause.
31 citations
,
January 1987 in “Dermatology” This study reports that topical minoxidil led to normalization of hair follicle characteristics in 36 of 47 severe alopecia areata patients, and indicated a shift in T cell populations, suggesting potential immunomodulatory effects.
31 citations
,
August 1986 in “Plastic & Reconstructive Surgery” This study found that using Dexon sutures led to significantly larger postoperative stretching and scar width compared to Prolene in patients undergoing scalp surgery for androgenetic alopecia correction.
30 citations
,
August 1998 in “International Journal of Dermatology” This study found that systemic corticosteroids led to satisfactory hair regrowth in 38.9% of severe alopecia areata patients, but hair fall occurred upon therapy discontinuation or tapering.
26 citations
,
October 2020 in “Pediatric Dermatology” This study found that oral tofacitinib led to clinically significant improvement in alopecia areata severity scores among pre-adolescents, though results varied and further evaluation in clinical trials is needed.
26 citations
,
November 2019 in “Medical Science Monitor” This study found that photobiomodulation via LED light at 630 nm and 810 nm increased proliferation and mineralization in osteoblast-like cells, with comparable effects between the two wavelengths.
26 citations
,
June 2018 in “Australasian Journal of Dermatology” Stopping sunscreen use on the forehead led to hair regrowth in a woman with frontal fibrosing alopecia.
24 citations
,
April 2017 in “JAMA Facial Plastic Surgery” This study found that facial rejuvenation surgery led casual observers to perceive patients as younger, more attractive, and more successful and healthy, suggesting significant societal benefits beyond a youthful appearance.
23 citations
,
June 1976 in “PubMed” This study observed that crash dieting led to significant hair loss in patients, with hair regrowth occurring several months after the diet.
22 citations
,
March 2012 in “Molecular Medicine Reports” This study found that DHT treatment led to reduced cell growth, increased cell death, cell cycle arrest, ROS production, and senescence in normal human dermal papilla cells, potentially mediated by altered miRNA expression.
20 citations
,
July 2024 in “Archives of Dermatological Research” This study observed that dupilumab led to significant hair regrowth and was well-tolerated in children with both alopecia areata and atopic dermatitis, showing promise as a safe treatment option for pediatric patients with associated atopy.
19 citations
,
August 2023 in “Journal of Dermatological Treatment” This case study reports that abrocitinib therapy led to clinical remission of alopecia universalis in a patient with a history of drug-induced DRESS, suggesting its potential as a treatment option.
18 citations
,
January 2015 in “International Journal of Trichology” This study found that intralesional steroid treatment led to significantly more hair regrowth in alopecia areata patients than narrow band ultraviolet B therapy, while their combination did not enhance effectiveness.
17 citations
,
March 1985 in “Acta Dermato Venereologica” This study found that 1% topical minoxidil led to an increase in terminal hair growth in some individuals with alopecia areata, but only one case showed cosmetically satisfying results.
15 citations
,
September 2005 in “The Journal of the American Animal Hospital Association/Journal of the American Animal Hospital Association” This study found that trilostane treatment led to complete hair regrowth in three Alaskan malamutes with ACTH-stimulated elevated 17-hydroxyprogesterone levels within 6 months without any recognized adverse effects.
10 citations
,
September 2013 in “Veterinary dermatology” This study found that medroxyprogesterone injections led to partial or complete hair regrowth in some Pomeranian dogs with alopecia X, though their IGF-1 levels remained unchanged.
8 citations
,
February 2017 in “Archives of Dermatological Research” This study found that IPL hair reduction led to significant decreases in hair count and thickness by promoting hair follicle miniaturization, increased telogen phase, and reduced cell proliferation.
8 citations
,
January 2017 in “Dermatology online journal” This case study reports that tofacitinib led to remission of psoriasis but did not improve alopecia universalis in one patient, suggesting varied responses in treating such conditions.
7 citations
,
June 2024 in “PubMed” This study found that bariatric surgery led to significant weight loss in patients, but it also resulted in complications like nutrient deficiencies, highlighting the need for dietary compliance and professional follow-up.
6 citations
,
August 1975 in “Journal of Endocrinology” This study found that cortisol and corticosterone led to thinning of the epidermis and hair follicle regression in fetal mouse skin, while testosterone promoted differentiation and sebaceous gland development.