The Hair Loss Encyclopedia

The Effects of Photobiomodulation on MC3T3-E1 Cells via 630 nm and 810 nm Light-Emitting Diode

November 2019 in “ Medical Science Monitor ”

Biao Chang, Haixia Qiu, Hongyou Zhao, Xi Yang, Ying Wang, Tengda Ji, Yuxuan Zhang, Qi Quan, Yunqi Li, Jing Zeng, Haoye Meng, Ying Gu

TLDR LED light therapy boosts bone cell growth and function.

The study investigated the effects of photobiomodulation (PBM) using 630 nm and 810 nm light-emitting diodes (LEDs) on MC3T3-E1 osteoblast cells. The research demonstrated that LED PBM enhanced cell proliferation, reduced apoptosis, and increased alkaline phosphatase (ALP) staining intensity and activity. Additionally, mineralization levels and mRNA expression of osteocalcin (OCN) and osteoprotegerin (OPG) were significantly elevated in irradiated cells compared to non-irradiated controls. The study concluded that both 630 nm and 810 nm LED PBM effectively promoted osteoblast activity, with no significant differences observed between the two wavelengths.

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Photodynamic and Photobiological Effects of Light-Emitting Diode Therapy in Dermatological Disease: An Update

research Photodynamic and Photobiological Effects of Light-Emitting Diode Therapy in Dermatological Disease: An Update

62 citations , July 2018 in “Lasers in Medical Science”

LED therapy is safe and shows potential for treating skin conditions and promoting hair growth, but more research is needed.

Activation of Wnt/β-Catenin Signaling Is Involved in Hair Growth-Promoting Effect of 655-nm Red Light and LED in In Vitro Culture Model

research Activation of Wnt/β-Catenin Signaling Is Involved in Hair Growth-Promoting Effect of 655-nm Red Light and LED in In Vitro Culture Model

19 citations , February 2018 in “Lasers in Medical Science”

Red light and LED treatments help hair grow by activating a specific cell signaling pathway.

Wnt/β-Catenin and ERK Pathway Activation: A Possible Mechanism of Photobiomodulation Therapy with Light-Emitting Diodes That Regulate the Proliferation of Human Outer Root Sheath Cells

research Wnt/β-Catenin and ERK Pathway Activation: A Possible Mechanism of Photobiomodulation Therapy with Light-Emitting Diodes That Regulate the Proliferation of Human Outer Root Sheath Cells

43 citations , September 2017 in “Lasers in Surgery and Medicine”

LED light therapy may help hair growth by activating certain cell pathways.

Comparison of the Effects of 665 nm Low-Level Diode Laser Hat Versus a Combination of 665 nm and 808 nm Low-Level Diode Laser Scanner on Hair Growth in Androgenic Alopecia

research Comparison of the Effects of 665 nm Low-Level Diode Laser Hat Versus a Combination of 665 nm and 808 nm Low-Level Diode Laser Scanner on Hair Growth in Androgenic Alopecia

24 citations , May 2017 in “Journal of Cosmetic and Laser Therapy”

The laser scanner device was more effective at increasing hair density than the laser hat in treating androgenic alopecia.

research Various Wavelengths of Light-Emitting Diode Light Regulate the Proliferation of Human Dermal Papilla Cells and Hair Follicles via Wnt/β-Catenin and the Extracellular Signal-Regulated Kinase Pathways

33 citations , January 2017 in “Annals of Dermatology”

LED light can help hair growth by activating specific cell pathways.

Low-Level Light Therapy for Androgenetic Alopecia: A 24-Week, Randomized, Double-Blind, Sham Device-Controlled Multicenter Trial

research Low-Level Light Therapy for Androgenetic Alopecia: A 24-Week, Randomized, Double-Blind, Sham Device-Controlled Multicenter Trial

106 citations , April 2013 in “Dermatologic Surgery”

Low-level light therapy safely improves hair growth and thickness for androgenetic alopecia.