Dupilumab Induces Hair Regrowth in Pediatric Alopecia Areata: A Real-World, Single-Center Observational Study

    Eden David, Neda Shokrian, Ester Del Duca … Emma Guttman‐Yassky
    Studysummary This study observed that dupilumab led to significant hair regrowth and was well-tolerated in children with both alopecia areata and atopic dermatitis, showing promise as a safe treatment option for pediatric patients with associated atopy.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on link.springer.com →
    Discuss this study in the Community →

    Research cited in this study 34

    1. Dupilumab Therapy for Alopecia Areata in a 4-Year-Old Patient Resistant to Baricitinib Frontiers in Medicine · 2023
    2. Associations Between Season, Climate, and Pediatric Alopecia Areata Flares in Providence, Rhode Island Archives of Dermatological Research · 2023
    3. Biomarkers in Alopecia Areata: A Systematic Review and Meta-Analysis Autoimmunity reviews · 2023
    4. Efficacy and Safety of Ritlecitinib in Adults and Adolescents With Alopecia Areata: A Randomised, Double-Blind, Multicentre, Phase 2b–3 Trial The Lancet · 2023
    5. Quality of Life in Children and Adolescents With Alopecia Areata: A Systematic Review Journal of the European Academy of Dermatology and Venereology · 2023
    6. Scalp Biomarkers During Dupilumab Treatment Support Th2 Pathway Pathogenicity in Alopecia Areata Allergy · 2022
    7. Impact of Pediatric Alopecia Areata on Quality of Life of Patients and Their Family Members: A Nationwide Multicenter Questionnaire Study Annals of Dermatology · 2022
    8. Maintenance, Withdrawal, and Re-Treatment with Ritlecitinib and Brepocitinib in Patients with Alopecia Areata in a Single-Blind Extension of a Phase 2a Randomized Clinical Trial Journal of the American Academy of Dermatology · 2021
    9. Influence of Climate Factors on Pediatric Alopecia Areata Flares in Philadelphia, Pennsylvania Scientific Reports · 2021
    10. Alopecia Areata: An Update on Etiopathogenesis, Diagnosis, and Management Clinical Reviews in Allergy & Immunology · 2021
    11. Dupilumab for the Treatment of Alopecia Areata in Children with Atopic Dermatitis JAAD case reports · 2021
    12. Treatment of Pediatric Alopecia Areata: A Systematic Review Journal of the American Academy of Dermatology · 2021
    13. Dupilumab Therapy for Alopecia Areata in Pediatric Patients with Concomitant Atopic Dermatitis Journal of the American Academy of Dermatology · 2021
    14. A Retrospective Study on Alopecia Areata in Children: Clinical Characteristics and Treatment Choices Skin appendage disorders · 2021
    15. The Alopecia Areata Investigator Global Assessment Scale: A Measure for Evaluating Clinically Meaningful Success in Clinical Trials British Journal of Dermatology · 2020
    16. Efficacy of Different Concentrations of Intralesional Triamcinolone Acetonide for Alopecia Areata: A Systematic Review and Meta-Analysis Journal of the American Academy of Dermatology · 2019
    17. Alopecia Areata: A Long-Term Follow-Up Study of 104 Patients JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology · 2019
    18. JAK Inhibitors for Alopecia Areata: A Systematic Review and Meta-Analysis JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology · 2019
    19. JAK Inhibitors and Alopecia Areata Lancet · 2019
    20. Janus Kinase Inhibitors for the Treatment of Severe Alopecia Areata: An Open-Label Comparative Study Dermatology · 2018
    21. An Integrated Model of Alopecia Areata Biomarkers Highlights Both TH1 and TH2 Upregulation Journal of Allergy and Clinical Immunology · 2018
    22. Prevalence of Pediatric Alopecia Areata Among 572,617 Dermatology Patients Journal of the American Academy of Dermatology · 2017
    23. Tofacitinib for the Treatment of Severe Alopecia Areata and Variants: A Study of 90 Patients Journal of The American Academy of Dermatology · 2016
    24. Safety and Efficacy of the JAK Inhibitor Tofacitinib Citrate in Patients with Alopecia Areata JCI insight · 2016
    25. A Systematic Review of Pulse Steroid Therapy for Alopecia Areata Journal of the American Academy of Dermatology · 2016
    26. Alopecia Areata Profiling Shows TH1, TH2, and IL-23 Cytokine Activation Without Parallel TH17/TH22 Skewing ˆThe ‰journal of allergy and clinical immunology/Journal of allergy and clinical immunology/˜The œjournal of allergy and clinical immunology · 2015
    27. Epidemiology and Burden of Alopecia Areata: A Systematic Review Clinical, Cosmetic and Investigational Dermatology · 2015
    28. The Association Between Interleukin-4 Gene Intron 3 VNTR Polymorphism and Alopecia Areata in Turkish Population Gene · 2013
    29. Early Stage Alopecia Areata Is Associated With Inflammation in the Upper Dermis and Damage to the Hair Follicle Infundibulum Australasian Journal of Dermatology · 2013
    30. Early Intervention with High-Dose Steroid Pulse Therapy Prolongs Disease-Free Interval of Severe Alopecia Areata: A Retrospective Study Annals of Dermatology · 2013
    31. Pulse Corticosteroid Therapy for Alopecia Areata in Children: A Retrospective Study Dermatology · 2013
    32. Case of Intractable Ophiasis Type of Alopecia Areata Presumably Improved by Fexofenadine The Journal of Dermatology · 2012
    33. Experimental Evaluation of Ebastine, a Second-Generation Antihistamine, as a Supportive Medication for Alopecia Areata Journal of Dermatological Science · 2010
    34. Intralesional Steroids for Alopecia Areata International Journal of Trichology · 2010