Successful Dupilumab Administration in an Adolescent with Alopecia Areata and Atopic Dermatitis: A Clinical Case

    September 2024 in “ Вопросы современной педиатрии ”
    Eduard T. Ambarchyan, Vladislav V. Ivanchikov, Anastasia D. Kuzminova … Liana R. Agliullova
    Studysummary This study reported that dupilumab led to significant reduction in skin rash severity and complete hair regrowth in an 11-year-old boy with severe alopecia areata and atopic dermatitis.
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    Research cited in this study 10

    1. TNF-α Inhibitor-Induced Psoriasis and Psoriatic Alopecia in an Adolescent with Ulcerative Colitis: Clinical Case Вопросы современной педиатрии · 2023
    2. Dupilumab Therapy for Alopecia Areata in a 4-Year-Old Patient Resistant to Baricitinib Frontiers in Medicine · 2023
    3. Efficacy and Safety of Ritlecitinib in Adults and Adolescents With Alopecia Areata: A Randomised, Double-Blind, Multicentre, Phase 2b–3 Trial The Lancet · 2023
    4. Dupilumab in Inflammatory Skin Diseases: A Systematic Review Biomolecules · 2023
    5. The Role of Antihistamines and Dupilumab in the Management of Alopecia Areata: A Systematic Review Journal of Drugs in Dermatology · 2022
    6. Dupilumab for the Treatment of Alopecia Areata in Children with Atopic Dermatitis JAAD case reports · 2021
    7. Immunological Properties of Atopic Dermatitis-Associated Alopecia Areata International Journal of Molecular Sciences · 2021
    8. Alopecia Areata: A Review on Diagnosis, Immunological Etiopathogenesis, and Treatment Options Clinical and Experimental Medicine · 2021
    9. An Integrated Model of Alopecia Areata Biomarkers Highlights Both TH1 and TH2 Upregulation Journal of Allergy and Clinical Immunology · 2018
    10. Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition Nature medicine · 2014