RU58841 is the only thing that worked for me, a DUPA sufferer
    Treatment 7/10/2025

    From the encyclopedia
    Finasteride →

    Frontline, gold standard treatment for combatting androgenic alopecia

    Minoxidil →

    An essential vasodilator with some anti-androgenic effects

    Dutasteride →

    Heavy duty finasteride that comes with higher risks

    At a glance
    In this treatment experience post, the primary subjects mentioned are
    💊 Finasteride (oral) 1.5 years
    💧 Minoxidil (topical) 6 months
    💊 Dutasteride (oral) 0.5mg 3 years
    💊 Minoxidil (oral) 6mg 1 year
    💧 RU58841 (topical) 8% 0.5ml after shower 8 months
    the tone is 😀 positive with slowed hair loss results.

    Other terms

    RU58841 was the only treatment that slowed hair loss and reduced irritation for a DUPA sufferer after trying finasteride, minoxidil, and dutasteride with no success. The user continues using 6mg oral minoxidil, 0.5mg dutasteride, and an 8% RU58841 solution.
    View this post in the Community →

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    6 / 6 results

      community Nearly Two Years of Min/Fin — 25M

      in Progress Pictures  124 upvotes 6 months ago
      The user has been using minoxidil and finasteride for nearly two years, seeing some prevention of further hair loss and possible regrowth. Many suggest trying dutasteride or considering a hair transplant as the next step.

      community 1.5 Year - Bad Results (HT, FIN, MINO, PRP, etc)

       64 upvotes 2 years ago
      A user shared their disappointing results after 1.5 years of hair treatments, including a hair transplant, finasteride, minoxidil, PRP, vegan shampoo, and more. They are considering switching to dutasteride, oral minoxidil, and improving their microneedling routine.

      community 24M - Dut + Min not working. How cooked am I?

       3 upvotes 10 months ago
      A 24-year-old is struggling with hair loss despite using treatments like dutasteride, oral minoxidil, RU58841, and considering a hair transplant. They are advised to continue medication, possibly increase dosages, and explore additional treatments like tretinoin and tacrolimus.

      community I don’t know what to do at this point

      in Female  87 upvotes 1 year ago
      A 21-year-old woman with female pattern baldness has tried minoxidil, red light therapy, and supplements without success. She is considering spironolactone and seeking medical advice.

    Related Research

    6 / 6 results
      Modern Ideas About Diffuse Alopecia

      research Modern Ideas About Diffuse Alopecia

      1 citations , May 2024 in “Effective Pharmacotherapy”
      This article reviews the causes, development, and treatment of diffuse alopecia, describing various external therapies and physiotherapy techniques.
      Pharmacotherapy for Diffuse Alopecia

      research Pharmacotherapy for diffuse alopecia

      1 citations , August 2021 in “Consilium Medicum”
      In this study, the use of Selencin, both in tablet and peptide lotion form, over two months showed significant improvements in reducing hair loss and restoring hair structure and volume in patients with diffuse alopecia, with effects persisting up to four months after treatment.
      Experience in Treatment of Diffuse Hair Loss

      research EXPERIENCE IN TREATMENT OF DIFFUSE HAIR LOSS

      August 2025 in “Vestnik dermatologii i venerologii”
      In this article, the authors concluded that despite diverse causes of diffuse hair loss, modern therapies can effectively manage the condition without side effects, as demonstrated in two clinical cases of telogen effluvium.
      Complex Application of High-Intensity Phototechnologies in the Treatment of Diffuse Alopecia

      research Complex application of high-intensity phototechnologies in the treatment of diffuse alopecia

      November 2024 in “Fizioterapevt (Physiotherapist)”
      In this study, a combined treatment method using fractional laser therapy, intravenous blood irradiation, and minoxidil significantly improved hair loss in patients with diffuse telogenetic alopecia compared to other treatments, showing a 36.9% improvement in mild cases and a 70.8% improvement in severe cases.