Quality of Life in Children and Adolescents With Alopecia Areata: A Systematic Review

    Mona Prendke, Varvara Kanti‐Schmidt, Doris Wilborn, Kathrin Hillmann, Rashmi Singh, Annika Vogt, Jan Kottner, Ulrike Blume‐Peytavi
    TLDR Alopecia areata significantly worsens quality of life in children, causing embarrassment and social issues.
    This systematic review evaluated the quality of life (QoL) in children and adolescents with alopecia areata (AA), encompassing 358 participants with AA and 64 healthy peers across 8 studies. The review found that AA significantly impaired QoL, with the most affected domain being embarrassment and self-consciousness. Additional psychosocial impacts included bullying and restricted participation in school or leisure activities. The findings highlighted the substantial impact of AA on children's QoL, emphasizing the importance of considering QoL as a key outcome in clinical practice and research for developing new treatments for pediatric AA.
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