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Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Odontogenic keratocysts are caused by abnormal Hedgehog signaling and can lead to tooth and bone issues.

Sox21 is crucial for tooth development and enamel formation by preventing cells from changing into a different type.

Facelifts for Asians are challenging due to thicker, heavier skin.

Both lasers are equally effective and safe for treating freckles.

Skin and its underlying fat layer act together to resist mechanical stress, and reinforcing this composite structure may help more with anti-aging than just strengthening the skin alone.

Different species use the same genes for tooth regeneration.

Papillon-Lefèvre Syndrome causes early tooth loss and skin issues, needing early dental diagnosis.

Caspases are enzymes important for both cell death and various non-lethal cell functions, affecting head development and hair growth, with different caspases playing specific roles.

Dogs have varying numbers of touch-sensitive Merkel cells in different skin areas, with most in the oral mucosa and facial skin, unrelated to age, sex, breed, or color.

Reflectance confocal microscopy is useful for diagnosing and monitoring skin diseases, but it has limitations and requires expertise for correct use.

Testosterone Replacement Therapy can improve sexual health in postmenopausal women with low sexual desire, but more research is needed on its long-term effects.

Ptch2 plays a key role in controlling stem cell function and the ability to regenerate after birth.

The document outlines steps for moving fat from one body part to another.

Hyaluronic acid injections can improve mouth opening and quality of life in scleroderma patients.

A woman developed a severe skin reaction after getting a birth control implant.

Autologous platelet concentrates show promise in esthetic treatments but need more standardized research.

Ultra-high-frequency ultrasound effectively evaluates the impact of hyaluronic acid fillers in reducing nasolabial fold wrinkles over time.

Most skin issues were due to COVID-19, with some caused by vaccines or treatments, and were categorized into five types.

A 7-month-old girl with a rare skin disorder died because diagnosis was delayed.

Using one's own blood platelets and fat can improve facial and hair appearance without surgery.

Successful outcomes depend on accurate diagnosis and strong doctor-patient relationships.

A 15-year-old girl has a skin condition causing blisters on her feet, likely inherited from her family.

Dermoscopy can non-invasively detect eruptive vellus hair cysts on the labia majora.

Menopause causes significant changes in the vaginal introitus, but less so in the labia majora, which may lead to symptoms of vaginal atrophy.

Sunekos® effectively improves labia majora appearance and is well-tolerated.

Vulvar acne, also known as "vulvar Fordyce adenitis", is a condition causing painful bumps on the labia, and it's not always effectively treated with common acne medications, but isotretinoin has shown promise.

Hair transplant surgery successfully restored a woman's pubic hair, improving her appearance and satisfaction.

A 68-year-old woman with benign mucous membrane pemphigoid has eye, mouth, and skin issues, including thick plaques and nail changes.