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This guide provides essential information for researchers working with laboratory mice, including husbandry, maintenance, ethical considerations, and resources for strains and data, emphasizing the importance of the 3Rs (replacement, reduction, and refinement) for humane research practices.

This study reported the development of new pyrazole-based MPC inhibitors that effectively inhibit mitochondrial pyruvate transport, showing potential as therapeutic candidates for conditions like metabolic dysfunction-associated steatohepatitis without activating PPARγ.

This study found that paxillin knockdown in human granulosa-derived cells and mouse models decreased androgen receptor protein levels and altered gene expression, suggesting paxillin's role in protecting against androgen excess effects, as observed in a polycystic ovary syndrome mouse model.

This article evaluates the therapeutic effects and safety of traditional herbal medicines used by tribal communities in India, but does not present new data or results.

This review discusses current knowledge about the TRPV3 ion channel's role in skin functions and diseases, highlighting its potential as a therapeutic target for pain and itch, though suitable ligands are limited.

This study identified various secondary metabolites such as terpenes, phenolic acids, and flavonoids in plants mentioned by Ibnu Sina for hair cosmetic applications.

This study suggests that finasteride may help alleviate high-fat diet-induced kidney damage in mice by reducing TMAO synthesis and regulating gut microbiota.

This article outlines how patient safety is integrated into the healthcare system, focusing on quality improvement and processes such as error reporting and root cause analysis, specifically for dermatologists.

This research paper reviews the mechanisms and management of non-biologic immunosuppressive drugs used in dermatology, highlighting their safety profiles and handling during pregnancy, breastfeeding, and vaccination, but does not report specific results on these aspects.

This abstract lists numerous dermatological side effects and reactions associated with various medications but reports no new research findings.

This research observed that translation initiation shifts from cap-dependent to IRES-mediated pathways varied across tissues and cell types under stress and differentiation conditions in mice, with low IRES/Cap ratios signaling high stemness and potential multipotency, mediated by the RNA processing protein PTBP1.

In a mouse model study, researchers found that mutations in Aire reduced alopecia areata frequency, while Notch4 mutations did not lead to the disease, likely due to proximity with a resistance gene.

This study found that acute stress can cause rapid hair loss by triggering necrosis in hair follicle cells and initiating autoimmunity, revealing a mechanism where stress-induced nerve activity leads to tissue damage and immune system activation.

In this study, S. chamaejasme extract applied topically to mice enhanced hair growth dose-dependently by increasing hair follicle size and dermal thickness, while upregulating mRNA expression related to hair growth, suggesting its potential as a hair growth treatment.

This review highlights how natural products with antioxidant properties can modulate the Wnt signaling pathway, potentially influencing various pathological conditions such as cancer, stroke, and regenerative medicine. It also addresses controversies in the compounds' mechanisms across different models and suggests research directions for future studies.

This study explored the in vitro skin penetration of two compounds from Tectona grandis leaf extract used for standardization and found that compound 1 penetrates more efficiently than compound 2, especially with a propylene glycol enhancer.

Intermittent fasting slows hair growth by damaging hair follicle cells.

The researchers highlighted that using nanomaterials for wound care could significantly improve healing by delivering antibacterial, antifungal, and anti-inflammatory effects, and may potentially reduce the economic burden associated with wound treatment.

This study identified two potent 5α-reductase inhibitors from Tectona grandis leaves, and suggests that ethanol is a preferable solvent for extracting these compounds, which are potential ingredients for hair loss treatments.

This study found that combining prodigiosin and essential oil from Thuja orientalis leaves showed a synergistic effect against the 3rd larva stage of Cx. pipiens, significantly reducing acetylcholine esterase activity and altering midgut pH, compared to untreated larvae.

The study reported that Demodex musculi infestation was notably higher in immunodeficient mice, while infested immunocompetent mice, particularly the BALB/c strain, showed increased IgE levels and developed alopecia over time.

This study found that programmed death-ligand 1 (PD-L1) levels correlated with the severity of alopecia areata, suggesting its potential as an indicator and possible target for new treatments.

Adalimumab significantly improves quality of life for patients with moderate to severe hidradenitis suppurativa.

This study introduced a novel framework that significantly improves the accuracy of alopecia areata lesion segmentation in semi-supervised scenarios, outperforming existing methods and aiding in the disease's diagnosis, treatment, and staging, which can impact quality of life and mental well-being.

This study introduced a new laser-only method called EKA for acne treatment, which is reported to be safe, painless, and heat-free, showing promising results for both acne and scar repair in initial sessions without combining with LED light.

In this case study, a Labrador dog diagnosed with hypothyroidism and treated with Thyroxine sodium, along with other supportive therapies, recovered completely from a generalized skin infection and alopecia within three months.

This study demonstrates that a proposed multi-stage framework improves the accuracy and faithfulness of drug-related responses generated by language models, compared to traditional methods.

This case study in a Labrador dog diagnosed with cutaneous lymphoma reports that treatment using the modified Wisconsin Madison protocol led to an uneventful recovery, despite the occurrence of vincristine-associated ileus, which was successfully treated with neostigmine.

In this study, researchers observed that knocking down the LPA 4 receptor in zebrafish embryos led to vascular and lymph vessel development abnormalities, including edema and decreased heartbeats.

A feedback loop between LRH and RSL4 controls root hair growth in Arabidopsis.