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This review summarizes recent findings on how the dysregulated PI3K/Akt/mTOR pathway contributes to immune-mediated inflammatory skin disorders and discusses the potential of natural products, synthetic compounds, and biologic agents in their treatment. However, it emphasizes the need for further research to develop effective therapies.

This article describes a unique case of lichen planopilaris with a previously unreported trigger in one of the youngest documented adult patients, without providing new clinical results or data.

This review discusses various patent articles on microemulsion carriers in drug delivery systems and reports no new empirical findings.

In this study, researchers developed a new method for producing dissolving microneedle array patches containing mesoporous silica nanoparticles, successfully confirming nanoparticle deposition and release in both ex vivo and in vivo models.

This study found that feeding mice a high-fat diet with fish oil leads to hair loss through a mechanism involving omega-3 fatty acids and TNF-α signaling, with epidermal fatty acid binding protein playing a key role.

In this study, a 6-month randomized controlled trial with postmenopausal women reported that supplementing with soy protein isolate with isoflavones led to significant improvements in skin hydration and reduced wrinkles and facial pigment intensity, but did not affect sebum production.

This book chapter discusses the mechanisms and prevention of selenium toxicity in livestock and reports no new experimental results; it emphasizes reducing selenium in the human food chain through animal products.

Evaluate and manage androgen excess in women with a systematic approach, considering both physical and psychological impacts.

This study revealed key cellular dynamics and interactions during early embryonic mouse skin development, highlighting complex transitions from precursor states to diverse multilayered structures.

This article explores the integration of nanotechnology and cosmetics, highlighting the development of cosmeceuticals targeting issues such as wrinkling, hyperpigmentation, and skin dehydration, while also reviewing cosmetic history and types of nanotechnology by particle size.

This research reports that copper-quercetin complexes show strong potential in antioxidation and cancer therapy, while their effects on specific cell death pathways warrant further investigation.

This review article outlines grooming practices and treatments for pseudofolliculitis barbae, noting that while discontinuing shaving is an effective approach, those who cannot do so may benefit from adjusted shaving techniques, chemical depilatories, or laser therapies.

This review found that both oral and topical soy-based products showed positive effects on various skin-related outcomes, including aging signs and skin barrier function, but topical applications were more likely to improve skin barrier status compared to oral supplementation.

This narrative review highlights the potential of naturally occurring compounds to target specific molecular pathways and overcome resistance in advanced and recurrent papillary thyroid cancer, offering new therapeutic possibilities beyond traditional treatments like surgery and lifelong hormone replacement.

In this study, researchers reported that adult females approaching menopause in Canada generally had similar or lower blood concentrations of toxic, essential, and trace elements compared to their peers, but most participants showed zinc levels below the proposed adequacy threshold.

This review from JAAD Reviews provides a comprehensive overview of hypertrichosis, discussing its diagnosis, treatment options like topical and laser therapies, and special psychosocial considerations for pediatric patients to better support clinicians and researchers in managing this condition.

In this study, researchers found that male and female APCHi mice exposed to ionizing radiation showed near-normal lipid and metabolite levels, suggesting activated protein C may offer some protective effects against radiation-induced damage affecting organ systems.

This review examines the growing global demand for diverse tea products, highlighting their health benefits and the economic challenges tea-producing countries face, while also exploring the rise of tea-based nutraceuticals, confectionery, toiletries, and cosmeceuticals.

This study found that washing hair with surfactants reduces the internal density of hair due to cuticle lifting, and suggests that a cuticle-sealing strategy can inhibit this effect and maintain hair homeostasis.

This study found that bacterially induced metabolic changes in stem cells can enhance skin and hair follicle regeneration in both mice and humans, suggesting potential strategies for improving recovery after injury.

This study adapted a method for culturing melanocytes from human hair follicles to horses, successfully creating partially melanotic equine melanocytes, potentially advancing hair follicle biology research across species.

This chapter discusses the composition, biocompatibility, and production methods of biomaterials like collagen, chitin, and silk for dermal substitutes, focusing on preclinical and clinical research, but reports no new clinical results.

In this study, radiofrequency microporation significantly improved topical minoxidil delivery and hair regrowth in a mouse model of androgenetic alopecia, with minimal systemic exposure compared to oral administration, suggesting it could be a promising needle-free option for topical therapy.

This review identified significant associations between glucose dysregulation and various dermatological conditions like psoriasis and acne, suggesting that dietary interventions and probiotics may help manage related inflammation, highlighting the need for holistic treatment approaches for insulin resistance and metabolic syndrome.

In this study, researchers observed that chronic stress affected wild-derived house mice differently by sex, with females showing less weight gain and distinct behavioral changes, while males exhibited higher hair corticosterone levels, suggesting divergent coping strategies and implications for sex-specific stress assessment protocols.

In this review, researchers reported that pyroptosis, a type of inflammatory cell death linked to inflammasome activity, is a key factor in the pathogenesis of alopecia areata and may present new therapeutic opportunities, though most treatments are still in early research stages.

In this study, chronic unpredictable stress affected male and female wild-derived house mice differently; stressed females gained less weight, had long grooming times, and lower immobility in tests, while stressed males showed increased hair corticosterone levels and shorter immobility times.

This study utilized a mouse model of traumatic brain injury to reveal that acute neurotrauma triggers widespread lipid metabolism reprogramming and storage lipid accumulation in microglial and monocyte populations, leading to lysosomal dysfunction, inhibited autophagy, and exacerbated inflammation through a pathological feedback loop.

This review found that in various dermatological diseases, skin microbiome diversity decreases, with an increased presence of pro-inflammatory strains, and suggests potential of prebiotic treatments as safer alternatives to antibiotics, though further research is needed to confirm efficacy.