Skin Microbiome Shifts in Various Dermatological Conditions

    August 2025 in “ Journal of Clinical Medicine
    Chau-Chin Lee, Mildred Min, Shumin Jin, Raja K. Sivamani
    TLDR Skin diseases alter the skin's microbiome, and prebiotic treatments might help.
    The review article examines the alterations in the skin microbiome linked to various dermatological conditions, noting a general decrease in microbial diversity and an increase in pro-inflammatory strains, particularly Staphylococcus aureus. Specific conditions like acne, atopic dermatitis, and androgenetic alopecia show distinct microbial shifts, such as increased Staphylococcus and Firmicutes in acne, and increased Cutibacterium acnes in androgenetic alopecia. The review suggests that prebiotic and probiotic treatments could be safer alternatives to antibiotics, which carry risks of toxicity and resistance. It emphasizes the need for further research to explore the potential of microbiome modulation in improving skin health and managing disorders.
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