Skin Microbiome Shifts in Various Dermatological Conditions

    August 2025 in “ Journal of Clinical Medicine ”
    Chau-Chin Lee, Mildred Min, Shumin Jin, Raja K. Sivamani
    TLDR Skin diseases alter the skin's microbiome, and prebiotic treatments might help.
    The review highlights significant alterations in the skin microbiome associated with various dermatological diseases, noting a decrease in microbiome diversity and an increase in pro-inflammatory bacterial and fungal strains, particularly Staphylococcus aureus. These changes provide insights into the development and progression of inflammatory skin conditions. The review suggests that prebiotic treatments could offer a safer and more cost-effective alternative to antibiotics, which pose risks of toxicity and antibiotic resistance. However, further research is needed to understand microbiome changes and evaluate the effectiveness of probiotic treatments in restoring the skin microbiome and improving patient outcomes.
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