September 2025 in “Cermin Dunia Kedokteran” This review highlights the importance of implementing dementia screening and cognitive evaluation in primary care to better prepare healthcare providers for managing cognitive impairment in the aging population.
13 citations
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January 2017 in “Molecules” This study reported that compounds isolated from Alpinia zerumbet significantly promoted hair cell growth and exhibited anticancer activity in cell cultures, suggesting potential as treatments for alopecia and cancer.
29 citations
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June 2018 in “Scientific Reports” In this study, Alox15 knockout mice exhibited disrupted skin integrity and increased inflammation, suggesting that Alox15-mediated resolvin D2 production is crucial for maintaining skin homeostasis by suppressing inflammation.
19 citations
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October 2024 in “BMC Medical Informatics and Decision Making” This study used machine learning models to analyze PCOS symptoms for early diagnosis, finding Support Vector Machine and VGG16 algorithms achieved high accuracy rates of 94.44% and 98.29% respectively.
278 citations
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March 2013 in “Gut” In this study, nearly 5% of anti-TNF-treated patients with IBD developed psoriasiform skin lesions, with smoking identified as a main risk factor, and ustekinumab proved highly effective in severe cases.
40 citations
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May 2018 in “PubMed” In this randomized, double-blind, placebo-controlled study, daily use of the Nutrafol® Women's Capsules nutraceutical significantly increased the number of terminal and vellus hairs and improved hair quality in women with self-perceived thinning over six months, without any reported adverse events.
28 citations
,
December 2008 in “Laboratory investigation” This study observed that selectively activating activin in the epidermis of mice enhanced reepithelialization during wound healing without altering the quality of the healed wound.
24 citations
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November 2003 in “The FASEB Journal” This study found that epimorphin and a modified peptide, pep7, can stimulate hair follicles to shift from a resting phase to a growing phase in both an organ culture assay and in mice.
21 citations
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January 2012 in “Biological and Pharmaceutical Bulletin” This study found that using a combination of iontophoresis and liposomal delivery facilitated the effective intradermal administration of superoxide dismutase in rats, reducing oxidative skin damage from UV exposure.
20 citations
,
November 2017 in “PubMed” This review discusses the potential benefits of a nutraceutical with biooptimized botanical extracts for treating hair loss and reports no new clinical results; ongoing studies aim to validate its efficacy.
19 citations
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February 2013 in “Journal of Investigative Dermatology” Touch domes in human skin are complex sensory structures not directly linked to hair.
16 citations
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September 2006 in “The Journal of Immunology” This study identified that mouse MILL1 and MILL2 are glycoproteins distinct from human MICA/B, primarily due to their association with β2-microglobulin and TAP-independent surface expression.
8 citations
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March 2019 in “Drugs - Real World Outcomes” This study reported that while general patient characteristics and adverse event incidence for eribulin were comparable between a healthcare claims database and post-marketing surveillance, significant differences in some side effects such as neutropenia were observed.
8 citations
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November 2017 in “PubMed” This article discusses common underlying mechanisms across hair loss disorders, emphasizing the role of inflammation, but reports no new clinical results.
8 citations
,
April 2011 in “Surgery today” This study found that sodium zinc dihydrolipoylhistidinate reduced chemotherapy-induced hair loss in rats, suggesting its potential as a treatment for this side effect.
3 citations
,
February 2023 in “International Journal of Molecular Sciences” This review discusses the composition, preparation, and applications of autologous platelet and extracellular vesicle-rich plasma, highlighting its potential benefits and the need for further research, but it reports no new clinical findings.
2 citations
,
January 1992 in “Neurologia medico-chirurgica” This study describes a new radiation method called three-dimensional moving field radiation therapy, which showed improved tumor targeting and reduced damage to surrounding tissues compared to traditional one-plane methods.
1 citations
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January 2012 in “Türk jinekoloji ve obstetrik derneði dergisi/Türk Jinekoloji ve Obstetrik Derneği dergisi” This study observed that over 90% of patients undergoing paclitaxel and platinum chemotherapy for certain gynecological cancers experienced significant, yet reversible, alopecia by the end of treatment.
1 citations
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February 2025 in “Skin Health and Disease” In this case study, a 39-year-old Japanese woman with severe alopecia areata demonstrated complete hair regrowth after one year using a combination of 0.5% delgocitinib ointment and excimer laser, suggesting potential efficacy and safety compared to conventional treatments.
In this reported case, a 30-year-old man with a long history of alopecia universalis experienced limited regrowth of eyebrows and eyelashes after six months of deuruxolitinib, despite unchanged scalp hair, suggesting site-specific potential for hair regrowth in challenging cases.
July 2024 in “Journal of Investigative Dermatology” CRISPR/Cas9 and prime editing can potentially fix skin disorder genes safely and effectively.
May 2024 in “Psychotherapie Forum” In this single-case study, researchers found that a combination of behavior and hypnotherapy led to positive psychological changes in a patient with Alopecia areata but did not result in hair regrowth, suggesting psychosomatic approaches may not address the hair loss mechanism.
This study found that conditioned media derived from dental pulp stem cells improved hair growth in 75% of men with androgenic alopecia, with positive results observed regardless of disease severity or the use of a dihydrotestosterone inhibitor.
This study observed two distinct groups of alopecia areata lesions based on PD-1 expression in T cells from biopsied skin samples, suggesting potential differences in subtypes or stages of the disease that warrant further investigation.
August 2019 in “Journal of Investigative Dermatology” This study found that tight junctions extend to the most superficial layer of the stratum granulosum in human skin, challenging previous claims of their limited presence in the epidermis.
January 2003 in “Dermatology” July 2026 in “Journal of Investigative Dermatology”
April 2023 in “Journal of Investigative Dermatology” This study found that in biopsied skin samples of alopecia areata, a lower anagen/telogen ratio was associated with increased T cell infiltration, and enhancing the PD-1/PD-L1 axis may inhibit CD8+T cell infiltration and improve the condition.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that infiltrating M2 macrophages promote wound-induced hair neogenesis in mice by producing growth factors that activate the wnt signaling pathway during the late phase of wound healing.