A Case of Refractory Alopecia Areata Successfully Treated by Combining Delgocitinib Ointment with Excimer Laser

    February 2025 in “ Skin Health and Disease ”
    Yukito Kakeji, Toshiaki Kogame, Yosuke Yagi … Kenji Kabashima
    Studysummary In this case study, a 39-year-old Japanese woman with severe alopecia areata demonstrated complete hair regrowth after one year using a combination of 0.5% delgocitinib ointment and excimer laser, suggesting potential efficacy and safety compared to conventional treatments.
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    Research cited in this study 7

    1. Real-Life Effectiveness and Safety of Baricitinib in Patients with Severe Alopecia Areata: A 24-Week Italian Study Journal of the European Academy of Dermatology and Venereology · 2024
    2. Successful Management of Severe Alopecia Areata and Vitiligo Using Topical Delgocitinib and a 308-nm Excimer Laser European journal of dermatology/EJD. European journal of dermatology · 2023
    3. Efficacy and Safety of Ritlecitinib in Adults and Adolescents With Alopecia Areata: A Randomised, Double-Blind, Multicentre, Phase 2b–3 Trial The Lancet · 2023
    4. Innate Type 2 Immunity Controls Hair Follicle Commensalism by Demodex Mites Immunity · 2022
    5. Alopecia Areata: An Update on Etiopathogenesis, Diagnosis, and Management Clinical Reviews in Allergy & Immunology · 2021
    6. Effects of UV-Induced Photoaging on the Hair Follicle Cycle of C57BL6/J Mice Clinical, cosmetic and investigational dermatology · 2021
    7. JAK Inhibitors for Alopecia Areata: A Systematic Review and Meta-Analysis JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology · 2019

    Related research 4

    1. Alopecia Areata: A Multifactorial Autoimmune Condition Journal of autoimmunity · 2018
    2. Linear Alopecia Areata JAAD case reports · 2018
    3. Treating Resistant Cases of Alopecia Universalis Journal of cosmetology & trichology · 2018
    4. Overview of Alopecia Areata ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2013