16 citations,
September 1990 in “Fertility and sterility” Ketoconazole can treat ovarian hyperandrogenism but should be used cautiously with monitoring and birth control.
14 citations,
May 2011 in “Drug Metabolism and Disposition” Ketoconazole increases finasteride's effectiveness and lifespan in the body.
12 citations,
March 2014 in “ISRN Pharmacology (Print)” Minoxidil with tretinoin boosts hair growth most effectively, followed by minoxidil alone, and then ketoconazole.
7 citations,
December 2019 in “Pharmaceutics” Taking Dutasteride with Ketoconazole can increase Dutasteride's effects and side effects.
2 citations,
May 2021 in “Research Square (Research Square)” Ketoconazole loaded solid lipid nanoparticles can penetrate skin better than regular drug suspension and marketed product, providing slow, sustained release and improved stability.
1 citations,
November 2023 in “Journal of cosmetic dermatology” The new anti-dandruff shampoo with ketoconazole-coated zinc oxide nanoparticles is more effective against dandruff.
1 citations,
November 2019 in “International Journal of Women's Dermatology” Ketoconazole shampoo can cause rare pink hair discoloration.
May 2024 in “Indian journal of pharmacy and pharmacology” Luliconazole is more effective than ketoconazole at repairing damaged hair cuticles.
May 2023 in “Asian journal of research in pharmaceutical sciences” Ketoconazole is effective for treating various fungal infections and has new uses in dermatology, but oral use can have serious side effects.
April 2021 in “Research Square (Research Square)” The new cocrystal KET-PABA is a more effective and safe anti-inflammatory treatment for skin conditions in mice.
September 2024 in “Journal of Clinical and Nursing Research” Combining Chuzhi Shengfa Tablets with ketoconazole shampoo or 5% minoxidil foam effectively promotes hair growth in men.
70 citations,
September 2017 in “Expert opinion on therapeutic patents” The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.
45 citations,
May 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.
89 citations,
May 1999 in “Allergy” The yeast Pityrosporum ovale can cause skin allergies and infections, and antifungal treatments like ketoconazole are effective against it.
28 citations,
December 2003 in “Medical Hypotheses” Ketoconazole shampoo with finasteride improves hair density in men with hair loss.
9 citations,
June 2019 in “Mycopathologia” Malassezia yeast linked to hair loss; ketoconazole helps treat it.
9 citations,
January 2008 in “Medical mycology” A dog's skin infection caused by the fungus Chaetomium globosum was effectively treated with ketoconazole.
2 citations,
January 1983 in “Archives of Dermatology” A 3-year-old boy's scalp infection was treated with ketoconazole.
2 citations,
December 2017 in “PubMed” A long-term pubic rash was finally diagnosed as white piedra and cured with ketoconazole.
1 citations,
January 2022 in “Advances in animal and veterinary sciences” Ketoconazole cream effectively treats fungal skin infections in cats.
1 citations,
September 2016 in “Veterinary dermatology” A combination of ciclosporin and ketoconazole can effectively treat severe hair loss in dogs.
1 citations,
February 2014 in “Revista de investigaciones veterinarias del Perú” A pet rabbit had a skin infection that was cured with ketoconazole.
June 2021 in “Current Biochemistry” Stingless bee propolis at a 6.25% concentration effectively stops dandruff-causing bacteria growth, performing better than ketoconazole.
December 2020 in “Jurnal RSMH Palembang (Online)” A man with a fungal scalp infection got better after treatment with griseofulvin, cetirizine, and ketoconazole shampoo.
Coconut oil and turmeric were almost as good as 2% ketoconazole shampoo for treating dandruff.
December 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” There are several promising treatments for hair loss, including dutasteride, latanoprost, ketoconazole shampoo, anti-androgens, laser/light treatment, and platelet-rich plasma, but more research is needed.
15 citations,
January 2009 in “Indian journal of dermatology, venereology, and leprology” Scalp white piedra can be treated with oral itraconazole and topical ketoconazole.
121 citations,
January 1991 in “Acta dermato-venereologica” Terbinafine quickly builds up in skin and hair, staying effective for over 3 weeks.
115 citations,
August 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Modulating Cytochrome P450 activity could help develop new skin disease treatments.
90 citations,
May 2019 in “Drugs” Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.