Ketoconazole Shampoo-Induced Hair Discoloration

    November 2019 in “ International Journal of Women's Dermatology ”
    Shelby L. Kubicki, Shadi Damanpour, Ranon E. Mann
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    TLDR Ketoconazole shampoo can cause rare pink hair discoloration.
    This article reports a case of hair discoloration in a 61-year-old African American female who used ketoconazole shampoo for non-scarring hair loss. The patient developed pink hair discoloration three weeks after initiating therapy with ketoconazole 2% shampoo. The pink color persisted despite use of multiple conditioning treatments. Light microscopic analysis of a hair sample showed red to pink particles adherent to the hair shaft. The article hypothesizes that the patient had a specific environmental exposure, such as contaminated water, with which FD&C Red No. 40 reacted. The article concludes that it is important to understand the potential adverse events associated with commonly prescribed topical medications such as ketoconazole in order to properly counsel patients and identify rare causes of hair discoloration.
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      in Research  828 upvotes 5 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
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      in Finasteride/Dutasteride  92 upvotes 1 month ago
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      community 3 Month Progress Pictures - Start -> Current

      in Progress Pictures  140 upvotes 4 months ago
      A user shared their 3-month hair loss treatment progress using 5% topical Minoxidil, Finasteride tablets, dermastamping, and ketoconazole shampoo. They reported significant improvement, advised consistency, and addressed questions about side effects and application methods.

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