Cutaneous Manifestations of Systemic Infection in Children

    Neil S. Prose, Steven D. Resnick
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    TLDR Skin symptoms are important for diagnosing infections in children.
    The document from 1993 reviews the cutaneous manifestations of systemic infections in children, covering a wide range of bacterial, rickettsial, spirochetal, and viral infections. It emphasizes the importance of clinical observation in diagnosing conditions such as staphylococcal scalded skin syndrome, Lyme disease, and various viral infections despite advances in laboratory diagnostics. The article discusses the systemic and cutaneous symptoms of infections like Toxic Shock Syndrome, Streptococcal Toxic Shock-Like Syndrome, and disseminated gonococcal infection, highlighting the importance of recognizing these signs for early diagnosis and treatment. It also describes the skin lesions associated with Pseudomonas septicemia, rickettsial infections like Rocky Mountain spotted fever, and congenital syphilis. Additionally, the document discusses the cutaneous signs of viral infections such as human parvovirus B19, human herpesvirus 6, and coxsackievirus A16, as well as the implications of HIV-1 and HTLV-1 infections in children. It underscores the necessity of timely diagnosis and treatment of these conditions to prevent serious complications.
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