Ketoconazole: A Promising Drug for Fungal Infections

May 2023 in “ Asian journal of research in pharmaceutical sciences ”

Rahul Jodh, Mukund Tawar, Gaurav Mude, Hitesh Khodaskar, Karishma Kinekar

ketoconazole topical ketoconazole hair loss adrenal sex hormone superficial fungal infections

TLDR Ketoconazole is effective for treating various fungal infections and has new uses in dermatology, but oral use can have serious side effects.

Ketoconazole, a synthetic imidazole antifungal agent, is effective in treating a variety of fungal infections such as surface fungal infections, genital candidiasis, chronic mucocutaneous candidosis, and dermatophytosis. It is unique among older imidazole antifungals in that it is effective when taken orally. It is also used to prevent fungal infections in immunocompromised individuals and has been used to treat advanced prostatic cancer due to its ability to inhibit adrenal sex hormone production. Despite oral ketoconazole having significant adverse effects leading to market withdrawal and labelling modifications, topical ketoconazole is deemed safe and effective, particularly for treating superficial fungal infections. New dermatologic uses for topical ketoconazole include treating onychomycosis, blepharitis, and hair loss.

View this study on ajpsonline.com →

Discuss this study in the Community →

Similar Research

5 / 1000+ results

research Female Pattern Alopecia: Current Perspectives

42 citations, August 2013 in “International Journal of Women's Health”

Female pattern hair loss is caused by multiple factors and while treatments like topical minoxidil, hormone therapy, and low-level light therapy can help, none can fully cure it.

research Hypotrichosis and Alopecia

July 2019

Accurate diagnosis and tailored treatments are crucial for managing hair loss in humans and animals.

research Treatment of Androgen Excess in Females: Yesterday, Today, and Tomorrow

9 citations, January 1997 in “Gynecological Endocrinology”

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

research Index

November 2019 in “Harper's Textbook of Pediatric Dermatology”

The document is a detailed medical reference on skin and genetic disorders.

research Systemic Antifungals: Overview, Applications, and Costs

January 2018 in “Springer eBooks”

Terbinafine is the most effective medicine for fungal nail infections, especially for diabetics and those with weak immune systems.

Ketoconazole: A Promising Drug for Fungal Infections

Related Community Posts Join

community Boys I am just a gonner. What on earth is my scalp even going through. Looks like world war 3. Pyril 3 months. Topical melitonin/progesterone/fin, dut, fin, oral min, laser trash, anus stimulation. Nothing. Donor area is decimated 😂.

community 5 Month's progress on Topical FIN, MIN, Topical Dut, Laser Cap

community This and ketoconazole 2% life changing

community What do these pictures say about my hair and scalp if anything? Miniaturization, inflammation, etc.?

community Treatment does not seem to be working