TLDR Luliconazole is more effective than ketoconazole at repairing damaged hair cuticles.
The study evaluated the effectiveness of luliconazole (LZ) and ketoconazole (KZ) in repairing damaged hair cuticles on 12 hair tresses, with 6 participants in each treatment group. After 5 and 10 washes, LZ-treated hair showed no cuticle upliftment and improved to grade 1 cuticle damage, while KZ-treated hair did not show improvement. SEM imaging and sensory analysis indicated that LZ treatment resulted in 2.42x and 2.72x improvements in hair smoothness and softness, respectively, after ten washes, compared to KZ. The study concluded that LZ, a botanical conditioner-based formulation, is more effective than KZ in enhancing hair integrity post-washing. The authors suggest that further human studies are needed to confirm these findings, and they disclosed that they are employees of Lupin Limited, which did not fund the study.
5 citations,
May 2021 in “International Journal of Cosmetic Science” Healthy scalp leads to better hair quality and less damage.
1 citations,
November 2019 in “International Journal of Women's Dermatology” Ketoconazole shampoo can cause rare pink hair discoloration.
26 citations,
April 2010 in “The American journal of dermatopathology/American journal of dermatopathology” Researchers created a standard system to grade hair damage using microscopic images.
32 citations,
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14 citations,
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39 citations,
January 2019 in “Journal of Dermatological Treatment” Ketoconazole cream is effective for skin conditions like seborrheic dermatitis and may help with hair loss and other skin issues, with generally mild side effects.
113 citations,
August 2016 in “Mycopathologia” New topical antifungals and delivery systems are improving treatment for fungal skin infections, but patient education and prevention are key.
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42 citations,
September 2018 in “Journal of Fungi” Terbinafine and itraconazole are more effective against Microsporum canis than fluconazole and griseofulvin.
