Effectiveness of Luliconazole vs Ketoconazole Topical Formulation in Reversing Damaged Hair Cuticle

    May 2024 in “ Indian journal of pharmacy and pharmacology ”
    Maneesha Khalse, Kamlesh Patel, Vasant N. Pawar
    Studysummary This in-vitro study reported that a luliconazole-based formulation improved hair cuticle integrity and was more effective than ketoconazole in repairing damaged hair after 5 and 10 washes, with sensory analysis supporting these results. Further human studies are needed to confirm its clinical effects.
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    Research cited in this study 6

    1. Prospective, Open-Label, Multi-Center, Randomized Study to Compare the Effectiveness, Safety, and Tolerability of Lulican Shampoo Versus Ketoconazole Shampoo in Indian Adult Patients With Mild to Moderate Scalp Seborrheic Dermatitis (LEAD Study) Cureus · 2022
    2. Role of Scalp Health in Achieving Optimal Hair Growth and Retention International Journal of Cosmetic Science · 2021
    3. Ketoconazole Shampoo-Induced Hair Discoloration International Journal of Women's Dermatology · 2019
    4. Development of a Classification System for Extrinsic Hair Damage: Standard Grading of Electron Microscopic Findings of Damaged Hairs ˜The œAmerican journal of dermatopathology/American journal of dermatopathology · 2010
    5. Senile Hair Graying: H2O2-Mediated Oxidative Stress Affects Human Hair Color by Blunting Methionine Sulfoxide Repair The FASEB Journal · 2009
    6. A Comparison of Hair Quality and Cosmetic Acceptance Following the Use of Two Anti-Dandruff Shampoos Journal of Investigative Dermatology Symposium Proceedings · 2005