research Some electron microscope observations on hardening in the human hair follicle
The hair follicle structure is more complex than thought, with new findings on protein formation.
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240-270 / 1000+ resultsresearch Structural features and sites of expression of a new murine 65 kD and 48 kD hair-related keratin pair, associated with a special type of parakeratotic epithelial differentiation
This study identified a new 65 kD and 48 kD keratin pair expressed in specific mouse epithelial sites, suggesting a unique evolutionary branch of hair-related keratins.
research Keratin expression in the normal nail unit: markers of regional differentiation
This study found that keratin expression patterns vary within nail unit structures, with the nail matrix uniquely expressing the acidic hair-type keratin Ha1.
research Cornification
This review discusses the cornification process of epidermal keratinocytes in forming the skin barrier and reports no new results; it emphasizes the importance for diagnosis and treatment of skin disorders.
research The Histology of Keratin Fibers
research Hard Keratin IF and Associated Proteins
research Modulation of the differentiated phenotype of keratinocytes of the hair follicle and from epidermis
This review examines the differentiation potential of epithelial cells from various sources in hair follicle formation, concluding that complex interactions are required for hair-specific characteristics, which were achieved in vivo but not in vitro.
research Human hair follicle cells of outer root sheath maintain their genuine keratin expression in vitro
research Single-cell transcriptomics defines keratinocyte differentiation in avian scutate scales
This study identified distinct gene expression programs in keratinocytes responsible for forming hard scales and soft interscale epidermis in chickens, revealing conserved differentiation genes similar to those in human skin.
research Specific Keratins and their Associated Proteins as Markers for Hair Follicle Differentiation
research Keratins and disease at a glance
This review discusses the role of keratins in providing mechanical resilience to epithelial tissues and highlights recent therapeutic approaches for keratin diseases, but reports no new experimental findings.
research Ultrastructural localization of hair keratins, high sulfur keratin-associated proteins and sulfhydryl oxidase in the human hair
Hair proteins change location and structure as hair cells mature.
research Expression of hair keratins in the adult nail unit: an immunohistochemical analysis of the onychogenesis in the proximal nail fold, matrix and nail bed
In this study, researchers identified the ventral matrix as the primary source of nail plate formation, while the dorsal portion is generated by the apical matrix.
research Keratins: Dynamic, flexible structural proteins of epithelial cells
Keratin proteins in epithelial cells are dynamic and crucial for cell processes and disease understanding.
research Structure and biochemistry of mammalian hard keratin
research Acidic and basic hair/nail ("hard") keratins: their colocalization in upper cortical and cuticle cells of the human hair follicle and their relationship to "soft" keratins.
This study found that specific human hair keratins are differentially expressed in the hair follicle, suggesting a shared pathway of epithelial differentiation between hair cortex and nail plate cells.
research The human keratins: biology and pathology
This review summarizes the cell type distribution and functional significance of human keratins, emphasizing their roles in tumor diagnosis and potential clinical applications, and reports no new clinical findings.
research Keratin Expression Provides Novel Insight into the Morphogenesis and Function of the Companion Layer in Hair Follicles
Keratin patterns in hair follicles help understand hair growth and potential hair and nail disorders.
research Keratin formation in the hair follicle
This study examined developing hair cortex with electron microscopy and found that keratin fibrils form between specific regions in hair follicles and aggregate into twisted cables.
research Crosslinking Between Trichocyte Keratins and Keratin Associated Proteins
research Keratin-mediated hair growth and its underlying biological mechanism
This study found that injecting keratin into the skin of mice promoted hair growth, potentially through keratin's interaction with hair-forming cells and changes in the microenvironment.
research Keratins and skin disease
Keratin mutations cause skin diseases and could lead to new treatments.
research Keratin 16 Expression Defines a Subset of Epithelial Cells During Skin Morphogenesis and the Hair Cycle
research Trichohyalin: A structural protein of hair, tongue, nail, and epidermis
research Immunohistochemical demonstration of keratins in the epidermal layers of the Malayan pangolin (Manis javanica), with remarks on the evolution of the integumental scale armour
This study demonstrates a varied distribution of keratins in the epidermis of the Malayan pangolin, suggesting evolutionary adaptations related to their distinctive scales.
research Keratin expression in mammalian skin, hair and nail [Abstract]
research Hair Keratin
research Assembly of Hair Keratins in Transfected Epithelial Cells
In this study, keratin genes mHa1 and mHb4 were unable to form an extensive keratin network in one cell line, altering endogenous keratin distribution, but showed better integration in another cell line.
research Generation of an immortalized human hair follicle keratinocyte cell line retaining trichogenic potential
research A Review: Different Types of Plants and its Extract Use in Hair Loss and Hair Growth Therapy
This review article reports that many herbal drugs show potential for treating alopecia effectively and with fewer side effects compared to synthetic drugs, addressing a common issue among urban residents due to stress and environmental factors.