Expression of Hair Keratins in the Adult Nail Unit: An Immunohistochemical Analysis of Onychogenesis in the Proximal Nail Fold, Matrix, and Nail Bed

    August 2004 in “ British Journal of Dermatology ”
    Christophe Perrin, Lutz Langbein, J. Schweizer
    Studysummary In this study, researchers identified the ventral matrix as the primary source of nail plate formation, while the dorsal portion is generated by the apical matrix.
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    Research cited in this study 12

    1. Androgen Regulation of the Human Hair Follicle: The Type I Hair Keratin hHa7 Is a Direct Target Gene in Trichocytes Journal of Investigative Dermatology · 2004
    2. The Catalog of Human Hair Keratins Journal of Biological Chemistry · 2001
    3. Characterization of a 300 Kbp Region of Human DNA Containing the Type II Hair Keratin Gene Domain Journal of Investigative Dermatology · 2000
    4. Keratin Expression in the Normal Nail Unit: Markers of Regional Differentiation British Journal of Dermatology · 2000
    5. The Catalog of Human Hair Keratins Journal of biological chemistry/˜The œJournal of biological chemistry · 1999
    6. A Novel Human Type II Cytokeratin, K6hf, Specifically Expressed in the Companion Layer of the Hair Follicle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998
    7. Characterization of a 190-Kilobase Pair Domain of Human Type I Hair Keratin Genes Journal of biological chemistry/˜The œJournal of biological chemistry · 1998
    8. Characterization of LHTric-1: A New Monospecific Monoclonal Antibody to Trichocyte Keratin Ha1 British Journal of Dermatology · 1997
    9. Cultured Nail Keratinocytes Express Hard Keratins Characteristic of Nail and Hair In Vivo Archives of dermatological research · 1992
    10. Patterns of Expression of Trichocytic and Epithelial Cytokeratins in Mammalian Tissues Differentiation · 1988
    11. Patterns of Expression of Trichocytic and Epithelial Cytokeratins in Mammalian Tissues II: Concomitant and Mutually Exclusive Synthesis of Trichocytic and Epithelial Cytokeratins in Diverse Human and Bovine Tissues (Hair Follicle, Nail Bed and Matrix, Lingual Papilla, Thymic Reticulum) Differentiation · 1988
    12. Acidic and Basic Hair/Nail (Hard) Keratins: Their Colocalization in Upper Cortical and Cuticle Cells of the Human Hair Follicle and Their Relationship to Soft Keratins ˜The œjournal of cell biology/˜The œJournal of cell biology · 1986

    Related research 6

    1. Expression of Hair Keratins in the Adult Nail Unit: An Immunohistochemical Analysis of Onychogenesis in the Proximal Nail Fold, Matrix, and Nail Bed British Journal of Dermatology · 2004
    2. Keratin 17 Expression in the Hard Epithelial Context of the Hair and Nail, and Its Relevance for the Pachyonychia Congenita Phenotype Journal of Investigative Dermatology · 2000
    3. Keratin Expression in Basal Cell Carcinomas British Journal of Dermatology · 1992
    4. Regulation of Keratin Gene Expression in Hair Follicle Differentiation Annals of the New York Academy of Sciences · 1991
    5. Expression of Keratin K14 in the Epidermis and Hair Follicle: Insights Into Complex Programs of Differentiation The Journal of Cell Biology · 1989
    6. A New Look Into an Old Problem: Keratins as Tools to Investigate Determination, Morphogenesis, and Differentiation in Skin Genes & Development · 1989