Some Electron Microscope Observations on Hardening in the Human Hair Follicle

The study reveals that the boundary between the outer and inner root sheaths of the hair follicle is more complex than previously thought, with Huxley's layer containing trichohyalin granules. It also identifies that the β-keratose fraction from oxidized wool and hair has both intra- and intercellular origins. Additionally, the research demonstrates the presence of fibrillar material in the keratinizing hair cuticle for the first time, prompting a reevaluation of fibrous protein formation in hair follicles.