3 citations,
May 2018 in “InTech eBooks” Animal models, especially mice, are essential for advancing hair loss research and treatment.
9 citations,
November 2020 in “The FASEB journal” Intermediate filaments are crucial for cell differentiation and stem cell function.
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October 2020 in “Veterinary Dermatology” New treatments and diagnostic methods for various animal skin conditions showed promising results.
10 citations,
January 2012 in “Journal of biomedical optics” Melanin density affects hair color, and this method can help in cosmetic assessments and diagnosing hair diseases.
13 citations,
May 2001 in “Current problems in dermatology” Keratin proteins in epithelial cells are dynamic and crucial for cell processes and disease understanding.
34 citations,
August 1966 in “Experimental cell research” Keratin fibrils in hair form and stop growing at specific points in the follicle.
27 citations,
November 2007 in “Genomics” Mutations in specific keratin genes cause improper hair structure in mice due to faulty keratin protein assembly.
186 citations,
December 2012 in “Current opinion in cell biology” Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.
189 citations,
July 2009 in “The Journal of clinical investigation/The journal of clinical investigation” Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.
13 citations,
May 2016 in “International journal of biological macromolecules” Keratin's mechanical properties are influenced by hydrogen bonds and secondary structure, and can be improved with the SPD-2 peptide.
109 citations,
September 2011 in “Human molecular genetics online/Human molecular genetics” New treatments targeting specific genes show promise for treating keratin disorders.
1 citations,
January 2013 in “Chronicles of young scientists” Immuno-cosmeceuticals from chicken egg yolk can effectively repair and improve damaged hair.
2 citations,
March 2023 in “BMC ecology and evolution” Some hair protein genes evolved early and were adapted for use in hair follicles.
30 citations,
December 2011 in “Journal of biological chemistry/The Journal of biological chemistry” Keratin 17 is modified by RSK1 in response to growth and stress, affecting skin growth and stress response.
January 2023 in “Indian dermatology online journal” A boy with Pachyonychia congenita has a confirmed gene mutation, highlighting the need for a local genetic database in India.
5 citations,
January 2022 in “Scientific reports” The research identified two types of keratinocytes in chicken scales: one for hard scales and another for soft skin, with similarities to human skin differentiation.
1 citations,
August 2024 in “Animals” KRT85 gene variations can help improve wool traits in sheep through selective breeding.
10 citations,
November 2016 in “International Journal of Cosmetic Science” A tough membrane between the outer and inner layers of human hair protects it from damage.
3 citations,
January 2021 in “Wear” Hair's resistance to wear varies by ethnicity and treatment, with less wear indicating stronger hair.
1 citations,
December 2015 in “The Egyptian Journal of Histology” Hypothyroidism harms rat skin, but topical triiodothyronine may help improve it.
24 citations,
December 2018 in “Life sciences” Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.
3 citations,
May 2018 in “Experimental Dermatology” Young HS patients often have other physical and mental health issues, and research on HS covers a wide range of topics including genetics, triggers, treatments, and the need for more data.
9 citations,
November 2018 in “Journal of cosmetic dermatology” Orobanche rapum extract rejuvenates skin and protects skin bacteria, leading to healthier skin.
72 citations,
July 2003 in “Journal of cosmetic dermatology” Frequent hair coloring and styling can damage hair and cause breakage or loss.
5 citations,
November 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Wnt/β-catenin signaling is important for keeping skin cell attachment structures stable.
6 citations,
October 2018 in “Drug safety - case reports” Alitretinoin may cause irreversible hair curling as a side effect.
188 citations,
June 1998 in “Molecular cell” Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.
[object Object] 42 citations,
June 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” PAI-2 helps in the maturation and protection of hair and nail cells.
14 citations,
July 2011 in “Clinics in plastic surgery” Dermabrasion is a safe, effective way to improve skin appearance with minimal recovery time.
August 2021 in “Annals of pathology and laboratory medicine” Most skin tumors in the study were benign, with squamous cell carcinoma being the most common malignant type.