12 citations,
January 2014 in “Cell structure and function” Different combinations of human hair keratins affect how hair fibers form.
178 citations,
May 2006 in “Developmental Dynamics” Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.
109 citations,
September 2011 in “Human molecular genetics online/Human molecular genetics” New treatments targeting specific genes show promise for treating keratin disorders.
87 citations,
July 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” Human beard hair medulla contains a unique and complex mix of keratins not found in other human tissues.
76 citations,
June 2015 in “Journal of biomedical science” Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.
54 citations,
January 2018 in “Scientific reports” Human hair contains diverse proteins, including keratins and histones, which could help assess hair health and aging.
54 citations,
November 2015 in “Methods in enzymology on CD-ROM/Methods in enzymology” Keratins are important for skin cell health and their problems can cause diseases.
38 citations,
October 2011 in “Analytical biochemistry” Hair proteins have weak spots in their α-helical segments.
36 citations,
November 2019 in “Molecular biology and evolution” Cysteine-rich keratins evolved independently in mammals, reptiles, and birds for hard skin structures like hair, claws, and feathers.
26 citations,
May 2014 in “BioEssays” Using neurohormones to control keratin can lead to new skin disease treatments.
17 citations,
June 2012 in “Journal of experimental zoology. Part B, Molecular and developmental evolution” Hair in mammals likely evolved from glandular structures, not scales.
14 citations,
April 2016 in “Cell Transplantation” Neural stem cell extract can safely promote hair growth in mice.
13 citations,
January 2020 in “Scientific Reports” The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.
13 citations,
December 2019 in “Nutrients” An apple-based supplement was found to stimulate hair protein production, which may help with hair growth.
8 citations,
July 2011 in “Animal science journal” Keratin 33A is a key protein in goat winter coats, especially in high-producing breeds.
7 citations,
January 2017 in “Biological & Pharmaceutical Bulletin” Certain compounds from Panax ginseng can block proteins that affect hair growth, potentially helping treat hair loss.
5 citations,
November 2008 in “Advances in Dermatology” The review highlights the importance of stem cells in hair health and suggests new treatment strategies for hair loss conditions.
January 2024 in “Frontiers in immunology” Histone modification is key in treating chronic inflammatory skin diseases.
Human hair keratins can self-assemble and support cell growth, useful for biomedical applications.
Keratin hydrogels from human hair show promise for tissue engineering and regenerative medicine.
June 2023 in “Journal of multidisciplinary sciences” PCOS may increase the risk of certain cancers.
June 2023 in “Journal of multidisciplinary sciences (Online)” PCOS is linked to a higher risk of endometrial cancer but not ovarian or breast cancer, and more research is needed on its role in cancer development and treatment effects.
22 citations,
August 2020 in “Cells” TGM3 is important for skin and hair structure and may help diagnose cancer.
2 citations,
May 2023 in “Cancer medicine” KRT80 may worsen cancer by increasing growth and spread, but its full effects on treatment and outcomes need more research.
2 citations,
April 2021 in “FEBS open bio” Human hair keratins K85 and K35 create unique filament patterns important for early hair formation.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin cells and certain hair follicle areas produce hemoglobin, which may help protect against oxidative stress like UV damage.
Protein profiling of forehead skin can help distinguish between frontal fibrosing alopecia and androgenetic alopecia.
January 2019 in “Applied Organometallic Chemistry” The compound (NH4)2Mn0.17Cu0.83Cl4.2H₂O has a specific structure, shows weak magnetism at low temperatures, and undergoes phase changes at high temperatures.