87 citations,
July 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” Human beard hair medulla contains a unique and complex mix of keratins not found in other human tissues.
10 citations,
February 2013 in “British Journal of Dermatology” Thyrotropin-releasing hormone may help control skin and hair growth and could aid in treating related disorders.
24 citations,
June 2018 in “Reviews in endocrine and metabolic disorders” Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.
28 citations,
April 1996 in “Cell biology international” Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.
March 2022 in “Research Square (Research Square)” 4-aminopyridine, a FDA-approved drug, speeds up skin wound healing and tissue regeneration.
November 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” 4-aminopyridine helps skin wounds heal faster and better.
11 citations,
November 1998 in “Journal of dermatological science” Knocking out certain genes in mice helps understand skin and hair growth problems.
438 citations,
October 2010 in “Oncogene” Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.
September 1998 in “Journal of The European Academy of Dermatology and Venereology” Topical 5α-reductase inhibitor helps counteract hair loss and stabilize it.
1 citations,
August 2021 in “International journal of scientific research in science and technology” The polyherbal hair oil promotes hair growth, reduces hair loss, and is safe to use.
2 citations,
May 2023 in “Cancer medicine” KRT80 may worsen cancer by increasing growth and spread, but its full effects on treatment and outcomes need more research.
13 citations,
May 2001 in “Current problems in dermatology” Keratin proteins in epithelial cells are dynamic and crucial for cell processes and disease understanding.
9 citations,
November 2020 in “The FASEB journal” Intermediate filaments are crucial for cell differentiation and stem cell function.
K15 and Id3 are important in hair follicle regeneration, with K15 increasing in early stages and Id3 responding later.
October 2014 in “Cancer research” Blocking mTORC1 reduces skin tumor growth in mice.
June 2006 in “Experimental dermatology” Hair follicle bulge cells are important for hair survival and help heal the skin after injury, which might be relevant for understanding hidradenitis suppurativa.
396 citations,
May 2011 in “Cell stem cell” Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.
84 citations,
January 2018 in “Biomaterials Science” Sericin hydrogels heal skin wounds well, regrowing hair and glands with less scarring.
78 citations,
June 2013 in “Science” Mice without the Sept4/ARTS gene heal wounds better due to more stem cells that don't die easily.
75 citations,
October 2016 in “Genes & Development” Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.
35 citations,
July 2018 in “Cell Reports” The study found that a specific area of the hair follicle helps start hair growth by reducing the blocking effects on certain cells and controlling growth signals.
20 citations,
November 2019 in “Stem Cells” Hes1 protein is important for hair growth and regeneration, and could be a potential treatment for hair loss.
6 citations,
December 2021 in “PLoS Genetics” Polycomb Repressive Complex 2 is not needed for hair regeneration.
August 2009 in “Mechanisms of Development” Adult hair follicle cells can create new hair follicles from corneal cells with the right support.
May 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” HPV8 causes hair follicle stem cells to grow, leading to skin lesions.
11 citations,
June 2019 in “Tissue & Cell” Hair stem cells produce a protein called COL17A1 that plays a key role in their development and is linked to hair thinning and baldness.
March 2024 in “Journal of biobased materials and bioenergy” Tea tree oil may help treat scalp alopecia by promoting hair follicle stem cell growth.
June 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Wnt ligand secretion by hair follicle cells is essential for hair growth and repair.
April 2012 in “Cancer research” Blocking mTORC1 may help prevent skin cancer by stopping the growth of certain skin stem cells.
10 citations,
August 2021 in “EMBO Reports” The Bcl-2 protein is important for keeping hair follicle stem cells working and preventing hair loss.