2 citations
,
May 2021 in “Stem Cells International” This study reviewed the progress in developing induced platelets from human stem cells as an alternative source to meet clinical demands, although challenges remain for large-scale production and clinical application.
62 citations
,
October 2016 in “Dermatologic Therapy” This study found that platelet-rich plasma was more effective for treating alopecia areata than topical 5% minoxidil, leading to earlier hair regrowth and reduction in hair abnormalities.
49 citations
,
August 2016 in “Aesthetic Surgery Journal” This study found that micro-needling with cosmeceuticals or platelet-rich plasma significantly improved wrinkles, skin laxity, scar softening, and hair growth over 12 months, with minimal side effects, and that the best results occur with pigment and platelet massaging between 5 to 30 minutes post-treatment.
27 citations
,
February 2023 in “Oxidative Medicine and Cellular Longevity” This study found that platelet-derived mitochondria can promote wound healing by reducing oxidative stress-induced apoptosis in vascular endothelial cells, with survivin identified as a potential target.
8 citations
,
August 2020 in “Experimental dermatology” This study observed that platelet-rich plasma samples from female patients show significant variability in growth factor secretion, which may influence the inconsistent clinical response in alopecia treatment.
April 2025 in “Russian Pediatric Journal” This review discusses the application of PRP therapy in pediatric settings and highlights the current lack of sufficient data for its widespread clinical use.
August 2024 in “OBM Transplantation” This article reviews the use of platelet concentrates in regenerative medicine and highlights the need for standardized protocols and more specific clinical studies, without reporting new clinical results.
January 2021 in “Research Square (Research Square)” This study observed that combining PRP with pro-angiogenic cells (Angio PRP) enhanced wound healing in a mouse model by promoting keratinocyte proliferation, angiogenesis, and vessel remodeling.
This study suggests that Sonic hedgehog from hair follicles may support the proliferation of dentate neural stem cells in mice through transport by platelets during the perinatal period.
December 2025 in “International Journal of Pharmacology” This review highlights that iPSC-derived artificial platelets offer a promising alternative to platelet-rich plasma for regenerative medicine, with standardized manufacturing and reproducible pharmacological properties, addressing variability issues associated with donor-derived platelets and showing therapeutic potential in preclinical models of osteoarthritis.
4 citations
,
February 2018 in “Journal of Cosmetic Dermatology” This study found that platelet-rich plasma injections increased hair diameter in the treated Pakistani population, with significant improvements observed in both men and women.
1 citations
,
October 1971 in “The BMJ” The document suggests that hair loss after stopping birth control may be similar to post-pregnancy hair loss and could recur with future pregnancies.
June 2024 in “Clinical and Experimental Obstetrics & Gynecology” In this study, women with recurrent implantation failure after IVF/ICSI had significantly lower platelet, plateletcrit, and lymphocyte counts, but these parameters were not effective for predicting the condition.
This review explores the clinical applications of platelet rich plasma therapies across several fields and suggests potential future research directions for cord blood platelet rich plasma.
The project developed and tested a method using plasma rich platelets to treat hair loss.
January 2023 in “Annali di stomatologia” This review traces the development and application of Platelet-rich Plasma in regenerative medicine, emphasizing its role in tissue healing and bone regeneration, but reports no new clinical results.
60 citations
,
December 2021 in “Cytokine & growth factor reviews” This review discusses the regenerative applications of platelet-rich plasma across various medical fields and reports no new clinical results, highlighting the need for further research into standardizing its preparation and use.
6 citations
,
April 2022 in “Cellular and Molecular Life Sciences” This study reports that a new protocol using Angio PRP improved wound healing in mice by enhancing key healing processes and regulating inflammation, suggesting potential for clinical advancements.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” 
April 2023 in “The Egyptian Journal of Hospital Medicine” The study found that intralesional injection of platelet-rich plasma appears safe and may be effective for treating post-burn scars, with shorter scar durations showing better results.
May 2022 in “Journal of advances in medicine and medical research” This study suggests that platelet-rich plasma (PRP) is effective when used with hair transplantation to treat cicatricial alopecia.
June 2020 in “Journal of Investigative Dermatology” This study found that platelet-derived growth factor secretion in PRP therapy for alopecia is highly variable between patients, which may contribute to inconsistent clinical responses.
2 citations
,
July 2024 in “Cureus” This review discusses the potential benefits of using autologous endometrial cells and PRP via hysteroscopic injections to improve pregnancy outcomes in ART, particularly in individuals with refractory thin endometrium, but reports no new clinical results.
July 2025 in “The Egyptian Journal of Hospital Medicine” This study concluded that preparing scars with either platelet-rich plasma or CO₂ laser significantly improved outcomes in hair transplantation for patients with cicatricial alopecia.
December 2021 in “Journal of V. N. Karazin Kharkiv National University: Series Medicine” In this study, treatment with platelet-rich plasma combined with 2% minoxidil was associated with normalization of immunohistochemical markers in patients with stage I-II androgenetic alopecia, suggesting potential for long-term therapeutic effects.
1160 citations
,
November 2018 in “Physiological Reviews” This review discusses the potential of single cell technologies to improve understanding and treatment of impaired wound healing and reports no new clinical results.
89 citations
,
January 2009 in “Advances in Clinical Chemistry” This review discusses the differences in wound healing between fetal and adult skin, highlighting the potential to uncover genes for scarless repair that could improve adult wound healing.
39 citations
,
November 1987 in “Clinica Chimica Acta” Human platelets change minoxidil to minoxidil sulfate, helping blood vessels widen.
17 citations
,
June 2016 in “Croatian Medical Journal” In this study, vitiligo and alopecia areata were more common among patients with chronic graft-vs-host disease than previously reported, linked to higher NIH skin scores and greater immunosuppressive treatment.