research Adverse Event Reporting in Clinical Trials of Finasteride for Androgenic Alopecia: A Meta-Analysis
Finasteride for hair loss may cause long-lasting side effects like impotence and low libido, but trials lack proper safety reporting.
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research Testosterone Therapy in Men: Clinical and Pharmacological Perspectives
Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.
research Exosomes Mediate Sensory Hair Cell Protection in the Inner Ear
Exosomes are crucial for protecting sensory hair cells in the inner ear.
research 5α-Reductase Inhibitors Increase Acute Coronary Syndrome Risk in Patients with Benign Prostate Hyperplasia
Taking both finasteride and dutasteride for prostate issues may raise the risk of heart problems.
research Study on the Zona Pellucida 4 (ZP4) Gene Sequence and Its Expression in the Ovaries of Patients with Polycystic Ovary Syndrome
The research suggests that the ZP4 gene is linked to egg development in women with PCOS but requires more study to understand its role in infertility.
research Characterization and Isolation of Stem Cell-Enriched Human Hair Follicle Bulge Cells
Researchers successfully isolated and identified key markers of stem cell-enriched human hair follicle bulge cells.
research Cardiovascular Risk Factors and Events in Women with Androgen Excess
Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.
research Cross-Sex Hormone Therapy for Gender Dysphoria
Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.
research Sexual Function in Women with Androgen Excess Disorders: Classic Forms of Congenital Adrenal Hyperplasia and Polycystic Ovary Syndrome
Women with congenital adrenal hyperplasia (CAH) have more sexual function issues than those with polycystic ovary syndrome (PCOS), but physical activity can improve sexual functioning in all women.
research Unveiling the Effect of Age and IgE Level on Alopecia Areata: Insights from Comparative RNAseq Analysis
Pediatric alopecia areata is more immune-active than adult cases, suggesting age-specific treatments and potential use of JAK inhibitors.
research Epidermolysis Bullosa Simplex: A Paradigm for Disorders of Tissue Fragility
Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.
research Dermatopathy in Juvenile Angus Cattle Due to Vitamin A Deficiency
Some young Angus cattle had skin problems due to not enough vitamin A, which got better after they were given more vitamin A.
research Androgenic Alopecia in a Postmenopausal Sicilian Baroness
The painting of an 18th-century Sicilian baroness shows she had hair loss, possibly due to ovarian issues, insulin resistance, or a specific type of tumor.
research Cutaneous Findings and Systemic Associations in Women With Polycystic Ovary Syndrome
Women with PCOS often have more body hair, acne, and skin darkening, and these signs are linked to metabolic issues like insulin resistance and high cholesterol.
research A Comprehensive Investigation of Biochemical Status in Patients with Telogen Effluvium: Analysis of Hb, Ferritin, Vitamin B12, Vitamin D, Thyroid Function Tests, Zinc, Copper, Biotin, and Selenium Levels
Telogen effluvium is linked to deficiencies in iron, vitamin B12, and thyroid function.
research Endocrine and Art: Why Diana Is Depicted with Mild Androgenic Alopecia?
Possible endocrine disorders caused woman's hair loss and obesity in painting.
research Relationship of Hypothyroidism with Alopecia Areata and Androgenetic Alopecia: Insights from a Two-Sample Mendelian Randomization Study
Hypothyroidism may cause certain types of hair loss.
research In The Quest To Stymie Time, Will Laboratory Data Stand Up In Man?
Genetic manipulations that extend lifespan in mice may not work as effectively in humans.
research How Effective Is Treatment With Antiandrogen Alone in Patients With Polycystic Ovary Syndrome?
Antiandrogens help manage PCOS symptoms but need careful monitoring.
research Neuropsychological Assessment in Elderly Men with Benign Prostatic Hyperplasia Treated with Dutasteride
Dutasteride does not impair mental function in elderly men with enlarged prostate.
research New Drugs Under Investigation for the Treatment of Alopecias
New treatments for hair loss show promise, but more research is needed to confirm their safety and effectiveness.
research The Roles of Exosomes in Regulating Hair Follicle Growth
Exosomes can help promote hair growth and may treat hair loss.
research Analysis of Skin Graft Survival Using Green Fluorescent Protein Transgenic Mice
GFP transgenic mice help study cell origins in skin grafts.
research ERG Induces Androgen Receptor-Mediated Regulation of SOX9 in Prostate Cancer
ERG increases SOX9, promoting prostate cancer growth and invasion.
research Hyperandrogenism from an Ovarian Interstitial-Cell Tumor in an Alpaca
An alpaca acted like a male and couldn't have babies because of a benign tumor in its ovary that caused high testosterone levels.
research Mommy, Where Do Tumors Come From? The Origins of Basal Cell Carcinomas
Some skin tumors may start from hair follicle stem cells.
research In Vivo Investigation in Pigs of Intestinal Absorption, Hepatobiliary Disposition, and Metabolism of the 5α-Reductase Inhibitor Finasteride and the Effects of Coadministered Ketoconazole
Ketoconazole increases finasteride's effectiveness and lifespan in the body.
research Thyroid Hormone Action in Epidermal Development and Homeostasis and Its Implications in the Pathophysiology of the Skin
Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.
research Relationship Between Betacoronaviruses and the Endocrine System: A New Key to Understand the COVID-19 Pandemic—A Comprehensive Review
Betacoronaviruses, like COVID-19, may cause hormone system dysfunction and affect disease susceptibility and severity.
research Synthesis and Structure–Activity Investigation of Iodinated Arylhydantoins and Arylthiohydantoins for Development as Androgen Receptor Radioligands
Scientists created iodinated arylhydantoins and arylthiohydantoins that could potentially be used for imaging prostate cancer. Some versions with specific side-chains showed high potential for this use.