How Effective Is Treatment With Antiandrogen Alone in Patients With Polycystic Ovary Syndrome?

    October 1998 in “ Journal of endocrinological investigation ”
    Evanthia Diamanti-Kandarakis
    TLDR Antiandrogens help manage PCOS symptoms but need careful monitoring.
    The document reviewed the effectiveness of antiandrogen treatments in patients with polycystic ovary syndrome (PCOS), focusing on drugs like spironolactone, flutamide, and cyproterone acetate. It found that antiandrogens could reduce hyperandrogenism and improve insulin sensitivity, though effectiveness varied. Potential side effects, such as hepatotoxicity with flutamide, were noted. Overall, antiandrogens were beneficial for managing PCOS symptoms but required careful monitoring.
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