TLDR Diane® is an effective contraceptive that also helps treat acne and mild hair growth issues.
The study evaluated Diane®, a combination of 2 mg cyproterone acetate (an antiandrogen) and 0.05 mg ethinyl estradiol, through extensive clinical trials. Diane® was found to be an effective contraceptive and a potent treatment for acne, seborrhea, and mild hirsutism. However, its impact on significantly increased hair growth was less pronounced. The paper also discussed the potential mechanisms of action of antiandrogens alone and in combination with estrogen.
7 citations,
May 1977 in “Deutsche medizinische Wochenschrift/Deutsche Medizinische Wochenschrift” Antiandrogen treatments can help with various women's health issues but often require ongoing use.
232 citations,
June 1975 in “Journal of Steroid Biochemistry” Cyproterone acetate is effective for acne but less so for hirsutism and alopecia, with some side effects and quick menstrual cycle recovery after treatment.
51 citations,
June 1970 in “British journal of dermatology/British journal of dermatology, Supplement” Antiandrogens may help treat conditions like excessive hair growth, prostate tumors, male baldness, and acne by blocking male hormone effects.
97 citations,
November 1986 in “Journal of Steroid Biochemistry” Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.
