April 2016 in “Journal of Investigative Dermatology” This study found that administering botulinum toxin A via Flex-PADs to mouse footpads inhibited sweating similarly to traditional injections, suggesting a promising patient-friendly delivery method for hyperhidrosis treatment.
January 2015 in “Indo American Journal of Pharmaceutical Research” This article describes mesotherapy, a technique involving small doses of compounds injected into the skin for cosmetic uses like aging skin and fat reduction, and provides no new clinical results.
May 2014 in “Journal of Investigative Dermatology” This article reviews recent imaging and genetic tool advances that enable in vivo study of hair regeneration and assessment of skin parameters, but it reports no new clinical results.
May 2014 in “Transfusion and Apheresis Science” PRP treatment showed no hair regrowth improvement after the first application in patients with alopecia.
April 2014 in “The FASEB Journal” This study found that platelet-rich plasma therapy may reduce hair loss and enhance growth in patients with androgenetic alopecia without noted side effects, although larger controlled studies are needed.
January 2013 in “Российский журнал кожных и венерических болезней” This article reviews the pathophysiology and limited effectiveness of current treatments for androgenic alopecia, including finasteride, minoxidil, botulinum toxin A, and platelet-rich plasma, and highlights the need for new therapeutic approaches; it reports no new clinical findings.
January 2013 in “Российский журнал кожных и венерических болезней” This study found that intradermal injections of group B vitamins and cystin B6 complex improved scalp circulation, supported hair growth, and reduced hair loss in patients with diffuse alopecia.
July 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” New treatment with Wnt proteins and growth factors safely increases hair thickness.
June 2004 in “Journal of Investigative Dermatology” Increased pigmentation may protect skin from UVB, new targets for skin disease treatments were identified, sunscreen ingredients don't affect hormones, TNF-α inhibitors may help diabetic wounds, and certain treatments could prevent chemotherapy-induced hair loss.
January 1998 in “Current Therapeutics” This article provides an overview of hair loss conditions and treatments, reporting no new research findings.
April 2026 in “Industrial & Engineering Chemistry Research” This study showed that keratinase pretreatment effectively reduces the time for enzymatic unhairing in bovine hides by opening channels for faster penetration, which shortens the process by over 50% and enhances leather quality.
November 2025 in “Contribuciones a las Ciencias Sociales” This study reported that a patient with androgenetic alopecia experienced significant improvements in hair density, thickness, and vitality using non-pharmacological approaches such as dietary adjustments, exercise, and supplementary treatments like low-level laser therapy and microneedling, suggesting these may be effective alternative management strategies.
January 2025 in “Anais Brasileiros de Dermatologia” This review examines male androgenetic alopecia and reports no new clinical results, offering insights to aid dermatologists in making informed therapeutic decisions.
April 2024 in “Medicina Estética Revista Científica de la Sociedad Española de Medicina Estética (SEME)” This study clarifies the fundamental aspects of intradermotherapy or mesotherapy, tracing its historical development and highlighting its benefits as well as the negative consequences of improper use, specifically addressing its decline due to severe side effects from treatment errors.
April 2023 in “Journal of Investigative Dermatology” This study found that intradermal injection of a specially designed RNA molecule, cp-asiAR, successfully reduced androgen receptor levels and promoted hair growth in a mouse model of androgenetic alopecia, while also improving hair follicle characteristics in ex vivo human scalp tissues without significant toxicity.
March 2023 in “Medica Hospitalia: Journal of Clinical Medicine” In this study, PRP treatment significantly promoted hair regrowth in patients with alopecia areata, with the best outcomes occurring after 4-6 sessions.
September 2022 in “International Journal of Trichology” In this study, microneedling and intralesional corticosteroid injections in patients with alopecia areata showed similar hair regrowth effectiveness, with microneedling resulting in more uniform but less dense regrowth and fewer side effects.
September 2022 in “Journal of The American Academy of Dermatology” In this study, the authors highlight the potential of intradermal microinjections of dutasteride as an adjunctive therapy for androgenetic alopecia, though they note that information on its effectiveness remains limited.
June 2022 in “IP Indian journal of clinical and experimental dermatology” This study found that both intradermal platelet-rich plasma and topical minoxidil with finasteride resulted in similar hair growth improvement in patients with androgenetic alopecia over 12 months.
January 2022 in “Journal of Cosmetic Dermatology” This study found that PRP injections, prepared using a digital centrifuge with a large-sized sodium citrate tube at low centrifugation speed, significantly improved hair thickness and terminal hair percentage in women with pattern hair loss, with similar results across different preparation methods.
December 2018 in “Вестник Российской Военно-медицинской академии” This study reported that platelet-rich plasma therapy significantly increased hair density and diameter in men with androgenetic alopecia by inducing morphological changes in hair follicles.
11 citations
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July 2017 in “Expert Opinion on Investigational Drugs” This review discusses current and emerging therapeutic strategies for androgenetic alopecia, noting limited evidence but suggesting areas such as prostaglandin analogs, PRP, and progenitor cell therapies as promising future directions.
1 citations
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April 2021 in “Annals of Otology Rhinology & Laryngology” This report highlights the diagnosis of a giant congenital blue nevus with secondary cutis verticis gyrata in a 20-year-old Asian male, underscoring the need for clinicopathologic correlation due to overlapping features with cerebriform intradermal nevi.
April 2024 in “MRIMS journal of health sciences” This study observed that autologous growth factor concentrate combined with topical minoxidil significantly improved hair growth and patient satisfaction in individuals with androgenic alopecia, with no adverse effects reported.
October 2015 in “CRC Press eBooks” This review discusses various surgical techniques for treating androgenetic and scarring alopecia and highlights the importance of understanding scalp anatomy and hair physiology, but it does not present new clinical results.
499 citations
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September 2011 in “Cell” This study found that intradermal adipocyte lineage cells in mice are necessary and sufficient to activate follicular stem cells, highlighting their role in regulating skin stem cell activity.
13 citations
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August 2016 in “Journal of Cosmetic Dermatology” This study found that intradermal injection of normal saline before follicular unit extraction significantly reduced wound size and skin mass removed compared to acute extraction, suggesting it minimizes skin injury in this procedure.
13 citations
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March 2013 in “The Laryngoscope” This study concluded that intradermal botulinum toxin type A injections are the preferred treatment for Frey's syndrome, with significant improvements in functional quality of life reported by patients.
7 citations
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January 2019 in “PeerJ” This study found that intradermal injection of Secreted Frizzled-related Protein 4 inhibits, but does not block, hair follicle regeneration in mice, suggesting potential therapeutic applications for hair follicle regeneration disorders.
6 citations
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May 2021 in “Aesthetic Surgery Journal” This study found that intradermal injections of platelet-rich plasma were equally safe and effective for treating androgenetic alopecia, with higher platelet numbers possibly enhancing hair density and follicle diameter.