How Can Frey's Syndrome Be Prevented or Treated Following Parotid Surgery?

    March 2013 in “ The Laryngoscope
    Robert L. Witt, Edmund A. Pribitkin
    TLDR Botulinum toxin type A injections are the preferred treatment for Frey's syndrome after parotid surgery.
    Frey's syndrome (FS), a common complication following parotid surgery, involves gustatory sweating and facial flushing due to nerve reinnervation. The study reviewed various prevention and treatment strategies, highlighting that FS is more prevalent with extensive parotid tissue removal. Interposition techniques, such as using muscle or fascial flaps, can reduce FS symptoms but are not foolproof and may involve complications. Botulinum toxin type A injections emerged as the most effective treatment, significantly improving quality of life with effects lasting up to 1.5 years, though repeat treatments may be necessary. While interposition grafts offer potential long-term prevention, their effectiveness beyond 3 years is unclear. The study emphasized the importance of parotid-sparing procedures and informed consent when using certain materials.
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