Intensive Dutasteride Mesotherapy Protocol With Oral Minoxidil as an Alternative to Antiandrogens in AGA: A Retrospective Analysis of a Hair Restoration Center

    Estefania Boland-Rodríguez, Cesar Daniel Villarreal-Villarreal, Abraham Benjamín Álfaro-Sánchez
    TLDR Combining dutasteride mesotherapy with oral minoxidil is more effective for hair loss than using oral minoxidil alone.
    A retrospective single-center pilot study at CEDAVI Derma experts in Monterrey, Mexico, investigated the efficacy of an intensive dutasteride mesotherapy protocol (IDMP) combined with oral minoxidil (OM) compared to OM monotherapy for treating androgenetic alopecia (AGA). The study included 105 patients, with 58 receiving OM monotherapy and 48 receiving OM plus monthly intradermal microinjections of dutasteride. Results showed a statistically significant improvement in the vertex area for the combination treatment group compared to the OM monotherapy group (P ≤ .001). The study concludes that IDMP enhances the effectiveness of OM in treating vertex AGA.
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