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This study found that fig leaf extract significantly downregulated inflammatory and androgenic gene expression in vitro, suggesting potential topical benefits for certain skin disorders.

This study found that specific gene upregulations and mutations in hidradenitis suppurativa skin support the role of inflammation, altered epithelial differentiation, and metabolism dysregulation in the disease's pathogenesis.

This study found that carbonic anhydrase II was significantly upregulated in human keratinocytes when treated with toll-like receptor 3 agonist and Th2 cytokines, suggesting its potential role in inflammatory skin conditions.

This study explores the potential connection between circulating cytokines and immune skin diseases, offering insights that may enhance understanding of their causes, diagnosis, and treatment approaches.

This review reports no new results but highlights the secretory function of keratinocytes, focusing on how various secretions, notably growth factors, impact stem cell differentiation into keratinocytes.

This review explores various topics related to skin diseases, hormones, receptors, growth factors, and therapeutic approaches, but it provides no new research findings.

This study found that Acanthus ebracteatus extract and verbascoside induced dermal papilla cell proliferation and reduced inflammatory cytokine release in vitro, suggesting potential for anti-hair loss applications.

This study found that transplanting hair follicles into human scars may remodel fibrotic tissue and reduce scarring by altering collagen structure and decreasing pro-fibrotic factors.

This meta-analysis found that alopecia areata patients had significantly higher serum levels of IL-6 and TNF-α compared to healthy subjects, indicating a potential role of these cytokines in the condition's pathogenesis.

This study found that treatment with EGFR inhibitors or mitogen-activated kinase inhibitors may compromise the immune privilege of human scalp hair follicles, suggesting new directions for managing drug-induced folliculitis.

This study found that topical application of Astragalus membranaceus extract induced hair regrowth and reduced immune response markers in mice with natural hair loss.

This study reviewed the role of inflammasomes in autoimmune skin diseases, highlighting their contribution to the pathogenesis of conditions such as vitiligo, alopecia areata, and psoriasis, and suggesting that targeting inflammasome dysregulation may offer new therapeutic options.

This study found that dietary yeast cell wall supplementation in broiler chickens increased certain immune responses compared to antibiotic treatments following immunization with sheep red blood cells.

This study reviews the complex keratinization process in the epidermis, detailing how various factors regulate keratinocyte differentiation and emphasizing the importance of understanding this process for the pathogenesis of skin disorders like ichthyoses and psoriasis.

This study found that alopecia areata is associated with distinct systemic and tissue immune signatures, with macrophages implicated as contributors to hair loss, suggesting potential therapeutic targeting of macrophage activity.

Copper may protect against alopecia areata, while certain inflammatory markers increase risk.

This study found a reciprocal correlation between depressive disorders and several dermatological autoimmune diseases, such as psoriasis and lupus, suggesting that inflammation may be a shared pathomechanism for these conditions.

This study found that patients with alopecia areata and their healthy family members had elevated levels of Th1- and Th17-related cytokines, suggesting a genetic link in cytokine dysregulation.

This study found that psoriatic skin lesions commonly express the cytokines IL-6, IL-8, and TNF-alpha along with a moderate presence of the antimicrobial protein defensin.

This review highlights the crucial role of the immune system in hair follicle regulation and its potential link to autoimmune disorders like alopecia areata. It suggests that understanding immune-mediated hair regeneration could lead to new treatments for this condition.

In this study, researchers found that children with alopecia areata exhibited immune system imbalances, including increased autoimmune and allergic markers and decreased phagocytic activity, along with a higher prevalence of autoimmune thyroiditis and allergic rhinitis compared to children without alopecia.

In a Phase II trial, Cox and colleagues reported that anti-IL17A therapy was well tolerated and led to a 64% reduction in wound size for venous leg ulcers unresponsive to standard treatments, although further validation in a larger trial is needed.

This study found that in mouse melanocytes, the cytoplasmic dynein complex component Dynlt3 is necessary for proper melanosome transport, acidity regulation, and effective transfer to keratinocytes, linking it to skin pigmentation processes.

This study found that Myrtus communis leaf extract significantly decreased IL-1α and increased VEGF gene expressions in human keratinocytes, which may relate to the plant's traditional uses for hair loss and wound healing, though further research is needed to explore these effects.

This study reviews the efficacy and safety of advanced therapies like TNFα inhibitors and IL-17/IL-23 inhibitors for dissecting cellulitis of the scalp, finding TNFα inhibitors particularly effective for severe or refractory cases, although prospective validation is needed for early intervention benefits.

This review synthesizes current evidence on therapies for dissecting cellulitis of the scalp, noting that biologics show promise for treatment-resistant cases, though systemic retinoids remain the first-line therapy.

In this study, researchers found that serum levels of integrin, CLEC10A, and interleukin-42 significantly differed between PCOS patients treated with infertility drugs and untreated PCOS patients when compared to healthy controls, suggesting these biomarkers could help differentiate treatment status in PCOS.

This study found that exosomes and secretome derived from rat hair follicle stem cells show promising potential for wound healing and tissue repair, demonstrating significant wound closure and suggesting their broader applicability in regenerative medicine.

In this study, thymic stromal lymphopoietin (TSLP) induced IL-4/IL-13 from T cells, prompting sebum secretion and adipose loss, suggesting IL-4/IL-13 may affect skin barrier function in atopic dermatitis.

This literature review explores the role of biomarkers in personalized medicine for various dermatological conditions like Hidradenitis Suppurativa, Psoriasis, and Atopic Dermatitis, highlighting how they guide targeted therapies and the limitations of current markers in specificity, as reported by the authors.