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Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

New treatments targeting the JAK signaling pathway, especially JAK inhibitors, show promise for alopecia areata.

Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

Parathyroid hormones are important for hair growth, but their use in treating hair loss from chemotherapy is still uncertain.

New treatments for hair growth disorders are needed due to limited current options and complex hair follicle biology.

MSC-derived exosomes can help treat COVID-19, hair loss, skin aging, and arthritis.

Early regulatory T cells are crucial for normal skin pigmentation.

A protein called EGFR protects hair follicle stem cells, and when it's disrupted, hair follicles can be damaged, but blocking certain pathways can restore hair growth.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

New effective scar treatments are urgently needed due to the current options' limited success.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Targeting CD200 could be a new treatment for rheumatoid arthritis.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Substance from human umbilical cord blood cells promotes hair growth.

Procyanidin compounds from apples and barley promote hair growth and prevent hair cell death.

The document concludes that individualized treatment for malignant epithelial tumors is necessary and more research on metastatic squamous cell carcinoma treatments is needed.

The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.

Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.

The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.