research SnapshotDx Quiz: May 2020 Study on BIVV009 in Bullous Pemphigoid
BIVV009 is a safe treatment for bullous pemphigoid that reduces C3 deposition without harmful side effects.
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research Dermal Papilla Cell-Derived Exosomes Regulate Hair Follicle Stem Cell Proliferation via LEF1
Exosomes from skin cells can boost hair growth by stimulating a gene called LEF1.
research Directed Elimination of Senescent Cells by Inhibition of BCL-W and BCL-XL
Blocking specific proteins can help remove aging cells and might treat age-related diseases and promote hair growth.
research The JAK/STAT Signaling Pathway: From Bench to Clinic
The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
research Reversible Activation of c-Myc in Skin
Activating c-Myc in skin causes rapid cell growth and changes, but these effects are reversible.
research Paracrine TGF-β Signaling Counterbalances BMP-Mediated Repression in Hair Follicle Stem Cell Activation
TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.
research Epidermal Notch Signaling: Differentiation, Cancer, and Adhesion
Notch signalling helps skin cells differentiate and prevents tumors.
research An Integrated Transcriptome Atlas of Embryonic Hair Follicle Progenitors, Their Niche, and the Developing Skin
The study identified unique genes in hair follicle cells and their environment, suggesting these genes help organize cells for hair growth.
research FGF5 Is a Crucial Regulator of Hair Length in Humans
FGF5 gene mutations cause unusually long eyelashes by affecting hair growth regulation.
research Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts During Wound Healing
Dermal fibroblasts have adjustable roles in wound healing, with specific cells promoting regeneration or scar formation.
research Role of Cytotoxic T Cells in Chronic Alopecia Areata
Cytotoxic T cells cause hair loss in chronic alopecia areata.
research Fibroblast State Switching Orchestrates Dermal Maturation and Wound Healing
Fibroblast state switching is crucial for skin healing and development.
research Endocannabinoids Limit Excessive Mast Cell Maturation And Activation In Human Skin
Endocannabinoids help control mast cell activity in human skin.
research Integument Pattern Formation Involves Genetic and Epigenetic Controls: Feather Arrays Simulated by Digital Hormone Models
Feather patterns form through genetic and epigenetic controls, with cells self-organizing into periodic patterns.
research The Structure and Organization of Lanceolate Mechanosensory Complexes at Mouse Hair Follicles
Lanceolate complexes in mouse hair follicles are essential for touch and depend on specific cells for maintenance and regeneration.
research Hidradenitis Suppurativa: A Practical Review of Possible Medical Treatments Based on Over 350 Hidradenitis Patients
Different treatments for Hidradenitis suppurativa range from antibiotics and hormonal therapies to surgery, depending on severity.
research Temporal Layering of Signaling Effectors Drives Chromatin Remodeling During Hair Follicle Stem Cell Lineage Progression
Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.
research Neural Potential of a Stem Cell Population in the Hair Follicle
Stem cells in hair follicles can become various cell types, including neurons.
research Activation of TRPV3 Regulates Inflammatory Actions of Human Epidermal Keratinocytes
TRPV3 in skin cells causes inflammation and cell death.
research Epidermal Stem Cells Do Not Communicate Through Gap Junctions
Epidermal stem cells don't use gap junctions to communicate.
research Going Below and Beyond the Surface: Microneedle Structure, Materials, Drugs, Fabrication, and Applications for Wound Healing and Tissue Regeneration
Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.
research Frontiers in Alopecia Areata Pathobiology Research
The review suggests that other immune cells besides CD8+ T cells may contribute to alopecia areata and that targeting regulatory cell defects could improve treatment.
research Recent Advances in the Structural Design of Photosensitive Agent Formulations Using Soft Colloidal Nanocarriers
New nanocarriers improve drug delivery for disease treatment.
research Proliferative and Non-Proliferative Lesions of the Rat and Mouse Integument
The project created a standardized system for classifying skin lesions in lab rats and mice.
research Inhibition of JAK-STAT Signaling with Baricitinib Reduces Inflammation and Improves Cellular Homeostasis in Progeria Cells
Baricitinib reduces inflammation and improves cell health in premature aging cells.
research Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata
MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.
research The Developmental Basis of Fingerprint Pattern Formation and Variation
Fingerprints form uniquely before birth due to specific genetic pathways and local signals.
research Activin B Promotes Epithelial Wound Healing In Vivo Through RhoA-JNK Signaling Pathway
Activin B helps heal skin wounds and grow hair by activating a specific cell signaling pathway.
research Hair Follicular Expression and Function of Group X Secreted Phospholipase A2 in Mouse Skin
sPLA2-X is crucial for normal hair growth and follicle health.
research Prevention and Treatment of Alopecia Areata with Quercetin in the C3H/HeJ Mouse Model
Quercetin effectively treated and prevented hair loss in mice.