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This study used machine learning to develop classifiers for identifying effective inhibitors of 5α-reductase isozyme 2, achieving high performance in distinguishing potent from weak inhibitors.

This study found that 62 plasma proteins are significantly associated with the risk of obstructive sleep apnea, offering potential targets for new therapeutic strategies.

In this study, the proposed MSF-VMDNet, combining dual encoder networks with a multi-frequency domain mechanism, significantly outperformed existing methods in segmenting skin cancer tissues from histological slide images, achieving high accuracy with an MIoU of 95.37% and a Dice coefficient of 95.11%.

This chapter provides an overview of the complex chemical and physical structure of the hair surface, detailing how factors like ethnicity, environmental stress, and cosmetic treatments can alter its properties and influence the adhesion of hair care products.

This study highlights that human hair follicle dermal papilla cells and glypicans play crucial roles in regulating hair follicle stem cell differentiation.

This study suggests that 20 vital medicinal herbs may exert therapeutic effects on alopecia by regulating specific target genes and proteins, offering insights into their novel mechanisms distinct from conventional drugs.

This study's network meta-analysis reported that botulinum injection combined with red laser and topical minoxidil is most effective for increasing hair density in androgenetic alopecia when using low-level laser therapy.

In this study on Angora rabbits, researchers identified genetic factors influencing wool fiber diameter by analyzing hair follicle proteins, highlighting keratin family members and other proteins as key contributors to fiber differences between coarse and fine wool.

This study reported that specific non-coding RNAs may regulate the hair follicle cycle in Angora rabbits by acting as competitive endogenous RNAs, enhancing understanding of ncRNA roles in hair growth.

This study found that the Qing Cuo Formula significantly reduced serum androgen and inflammatory cytokine levels in hamsters with damp-heat acne and identified potential molecular mechanisms and active compounds involved.

This review examines emerging biomaterial strategies designed to support both neural regeneration and cutaneous wound healing, emphasizing their potential to improve sensory function through mechanisms like axonal regrowth and vascular network formation, while noting the need for standardized assessments and clinically translatable designs.

This review discusses neuroimmune communication in skin disorders and peripheral neuropathic pain, highlighting the complex interactions between sensory neurons and immune cells; it reports no new clinical results but suggests potential future therapies.

This review suggests that curcumin and piperine may offer a promising multi-target therapeutic approach for alopecia by simultaneously modulating androgenic and inflammatory pathways, though experimental and clinical validation are necessary to confirm their efficacy.

In this review, researchers explored the potential of a curcumin–piperine combination in alopecia management through computational analyses, highlighting its capacity to modulate multiple pathways involved in hair follicle homeostasis, although further experimental and clinical validation is necessary to confirm its efficacy.

This research by Yuan et al. focused on developing a comprehensive human skin cell atlas, analyzing various cell types and diseases, and introduced a deep learning method, scSEA, for unbiased reference mapping, potentially discovering new cell types.

The researchers developed a comprehensive human skin cell atlas using data from various studies and established a consensus nomenclature for normal human skin in this project, which also includes a deep learning-based method for more effective reference mapping of new cells.

This research reported that melatonin may serve as a potential treatment for both rosacea and Alzheimer's disease by regulating inflammation and vascular signaling pathways, demonstrating effectiveness in reducing symptoms associated with rosacea-like skin lesions in experimental settings.

This study analyzed gene expression in Pashmina goats and identified key biological processes and molecular functions involved in long-fibre production, suggesting potential pathways for enhancing this trait in other goat breeds.

This study found that the combination of TTNPB and CHIR99021 enhanced the derivation of highly advanced neural stem cells from human pluripotent stem cells, with improved chromatin accessibility and neuroectodermal gene expression, and these cells successfully engrafted in rat hippocampi to ameliorate depression-like symptoms.

This study analyzed circular RNA expression in the developing skin of foetal Gansu Alpine fine-wool sheep, identifying key circRNAs potentially involved in secondary follicle development through regulatory networks, providing insights for wool trait improvement.

This article reviews the regulation of androgens in human skin and adrenals, highlighting their role in skin disorders, but reports no new research findings.

This study found that the binding and release of BMP-2 from kerateine biomaterials are significantly influenced by pH and salt concentration, highlighting the potential for developing improved bone repair systems.

This study examined the structural and biochemical mechanisms of human lipocalin prostaglandin D synthase, detailing substrate and product binding processes at the catalytic site and suggesting potential for drug delivery targeting hydrophobic molecules.

In this study, WNT10A was identified as a key gene in the development and maturation of skin hair follicles in fetal Inner Mongolian cashmere goats.

This study identified a coexpression network and key genes associated with thyroid eye disease, potentially aiding in its treatment and diagnosis.

This study proposed a new approach to combat leishmaniasis by targeting host proteins rather than the parasite itself, identifying eight existing drugs as potential treatments despite not having been previously tested on leishmaniasis.

In this study, researchers demonstrated that human hair keratins can self-assemble into stable nanofibrous networks in vitro, which are compatible with human skin cells and useful for regenerative applications.

Ro stress hindered ginseng root growth and ginsenoside production, but increased certain hormones and affected gene regulation related to plant growth and stress responses.

This review discusses the growing role of colorimetric sensors in food safety, highlighting their potential to enhance detection accuracy and manageability, while also noting challenges such as environmental interference and the need for further industrial validation.

This study reported that a new coating made with delaminated Ti₃C₂ MXene nano-sheets and a tea-derived compound effectively protects hair keratin from damage by providing UV screening, thermal dissipation, and antioxidation, while also enhancing mechanical strength and restoring wettability.