60 citations,
September 2001 in “Journal of the American Academy of Dermatology” Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.
27 citations,
December 2016 in “Dermatology and Therapy” Certain skin conditions can indicate insulin resistance and should prompt lifestyle changes and medical treatment to manage underlying health issues.
26 citations,
January 2000 in “Hormone research in paediatrics” Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.
17 citations,
May 2019 in “Diabetes and Metabolic Syndrome: Clinical Research and Reviews” High fasting insulin levels in women with PCOS are linked to a higher risk of heart and metabolic problems.
17 citations,
December 2008 in “Dermatology” Taking metformin with intense-pulsed-light therapy improves hair removal for people with PCOS.
11 citations,
July 2016 in “Endocrinology” Higher Lnk protein levels in ovaries may lead to insulin resistance in women with PCOS.
7 citations,
January 2015 in “Case reports in endocrinology” The document concludes that HAIR-AN syndrome should be considered when a patient shows severe hyperandrogenism and insulin resistance after excluding tumors.
November 2004 in “John Wiley & Sons, Ltd eBooks” Insulin resistance is linked to PCOS and can lead to other health issues, but treatments like metformin can help manage symptoms.
The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.
343 citations,
December 2008 in “Endocrine Reviews” Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
66 citations,
September 2008 in “Dermatologic therapy” The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.
249 citations,
November 2003 in “Clinical endocrinology” Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.
200 citations,
October 2009 in “European journal of endocrinology” Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.
60 citations,
February 2010 in “Gynecological Endocrinology” Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.
14 citations,
September 2017 in “Clinics in Dermatology” Skin diseases linked to insulin resistance should be managed to prevent diabetes and reduce heart disease risk.
11 citations,
April 2019 in “International Journal of Molecular Sciences” Certain genetic variations in OCT1 may improve insulin sensitivity with metformin in women with PCOS.
1 citations,
August 2023 in “Curēus” Metformin helps reduce PCOS-related infertility by improving insulin sensitivity and inducing ovulation.
1 citations,
January 2022 in “Journal of experimental and clinical medicine” PCOS is linked to diabetes and insulin resistance, and managing AGEs may help treat related symptoms.
1 citations,
June 2019 in “Innovare journal of medical sciences” Polycystic Ovary Syndrome (PCOS) is a hormonal disorder in women that can cause infertility and other health issues, and it may be improved by treatments that increase insulin sensitivity.
1 citations,
June 2017 in “International journal of reproduction, contraception, obstetrics and gynecology” N-acetylcysteine was more effective and had fewer side effects than metformin for improving insulin resistance in women with PCOS.
August 2015 in “Postgraduate obstetrics & gynecology” Women with PCOS often have metabolic issues like insulin resistance and a higher risk of diabetes and abnormal lipid levels.
7 citations,
November 2003 in “Current Opinion in Obstetrics & Gynecology” Metformin helps improve symptoms and reproductive outcomes in people with polycystic ovary syndrome.
28 citations,
November 2007 in “Medical Clinics of North America” Obesity worsens Polycystic Ovary Syndrome symptoms, and weight loss is a key treatment.
21 citations,
January 2003 in “Seminars in reproductive medicine” The document concludes that various drugs can manage symptoms and metabolic issues in women with PCOS.
May 2022 in “Maǧallaẗ Buḥūṯ Al-Tarbiyyaẗ Al-Nawʿiyyaẗ (Print)” Eating a high inositol diet significantly improves insulin resistance and hormone levels in women with PCOS.
169 citations,
August 2004 in “Baillière's best practice & research. Clinical obstetrics & gynaecology/Baillière's best practice and research in clinical obstetrics and gynaecology” Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.
54 citations,
August 2017 in “Gynecological Endocrinology” Lifestyle changes and weight loss are key for treating PCOS-related metabolic issues and infertility, with various medications available for specific symptoms.
991 citations,
January 2011 in “Nature Reviews Endocrinology” The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.
883 citations,
August 2016 in “Nature Reviews Disease Primers” Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.
467 citations,
October 2014 in “European Journal of Endocrinology” The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.