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Metformin should be used for PCOS mainly in those with glucose intolerance, and has limited benefits for infertility or hirsutism.

This review discusses the therapeutic use of insulin-sensitizing agents in polycystic ovary syndrome, reporting improved ovulation, insulin sensitivity, and reduction of hyperandrogenism, but calls for larger studies to confirm these effects.

This narrative review suggests that nutraceutical insulin-sensitizing agents like myo-inositol, alpha-lipoic acid, and vitamins may improve glycemic control and reduce inflammation in insulin resistance-related skin disorders; however, more robust long-term trials are needed to confirm these findings and establish treatment regimens.

This review discusses recent advances in understanding acne pathobiology, highlighting the potential for developing new customized therapies, but it reports no new clinical findings.

This review examines the best available evidence for diagnosing and managing PCOS but reports no new clinical results.

This article reviews management strategies for PCOS and reports no new clinical results; the authors highlight oral contraceptives, lifestyle modifications, and metformin as key interventions.

This review discusses the dermatologic features of PCOS as potential early indicators of the syndrome and notes that treatment of these conditions may enhance quality of life and psychological well-being, but it reports no new clinical results.

This review discusses the dermatologic manifestations of hyperandrogenism in women and outlines the diagnostic approach and treatment options, reporting no new clinical results.

This article reviews the hormonal pathogenesis and treatment strategies for acne vulgaris, particularly in women with severe or treatment-resistant cases, associating it with hormonal imbalances and hyperandrogenism.

This review discusses the causes, clinical features, diagnostic approach, and treatment options for hirsutism in women, but reports no new findings.

This article examines current pharmacologic treatments for PCOS focusing on symptom-specific approaches, particularly the metabolic effects of therapies, but reports no new clinical findings.

This article provides an endocrine perspective on evaluating and managing hirsutism but reports no new research findings.

This article discusses the importance of recognizing polycystic ovary syndrome in adolescent girls during initial evaluations of menstrual irregularity and outlines current treatment strategies, reporting no new clinical results.

This review discusses symptom-driven treatment approaches for PCOS, focusing on ovulation induction, androgen reduction, and weight management, and reports recent advances like recombinant FSH and GnRH-agonist protocols without providing new clinical results.

This review discusses current and emerging therapeutic strategies for managing polycystic ovary syndrome, emphasizing treatment tailored to individual patient complaints and highlighting the roles of hormone therapy and insulin-sensitizing agents.

This review summarizes the current knowledge on polycystic ovary syndrome, including its features, diagnosis, and treatment, and highlights the need for further research to fill existing knowledge gaps.

This review discusses the prevalence and management of polycystic ovary syndrome in women, particularly noting gaps in understanding its presence in adolescents, and reports no new clinical findings.

This article discusses the diagnosis and treatment options for hirsutism and reports no new clinical findings.

This review highlights that while lifestyle changes may help with many ovulatory disorders, oocyte donation is considered a viable option for patients who cannot undergo ovulation induction; it reports no new results.

This article discusses hirsutism, a condition causing excessive hair growth in women, and offers no new clinical results.

This systematic review reports that HAIR-AN syndrome, characterized by severe insulin resistance, hyperandrogenism, and distinctive skin issues, significantly impacts obese women and can improve with treatments like metformin, emphasizing the importance of targeted management to reduce metabolic complications.

This study highlights that polycystic ovary syndrome develops through genetic and environmental factors, with insulin resistance as a key mechanism, impacting the risk of metabolic and cardiovascular conditions.

This article reviews current understanding and management strategies for polycystic ovary syndrome, emphasizing lifestyle changes alongside medical treatment, and reports no new clinical results.

Women with PCOS often have insulin resistance, abnormal lipid levels, and a higher risk of diabetes and heart disease; lifestyle changes and medication like metformin can help manage these risks.

This chapter reviews various treatments for hirsutism, including antiandrogens, finasteride, eflornithine, and epilation methods, but reports no new clinical results.

This review discusses the symptoms, diagnosis, and management of polycystic ovarian disease, emphasizing the complex implications of obesity and insulin resistance, and calls for long-term follow-up to assess management strategies.

The book provides a clear overview of PCOD and is recommended for medical trainees and clinicians, but may lack depth for advanced researchers.

This review discusses various anti-androgen treatments for hirsutism, including androgen receptor blockers and inhibitors, and emphasizes the role of diagnosis in selecting the most appropriate therapy, but reports no new clinical results.

This article reviews current treatment options for acne, hirsutism, and androgenetic alopecia in women with PCOS, recommending individualized and multidisciplinary approaches, but reports no new clinical results.

This review discusses the use of insulin-sensitizing agent metformin for treating PCOS in adolescents, noting potential benefits but emphasizing the need for more rigorous trials due to current study limitations.