The Polycystic Ovary Syndrome and Acne

    January 2014 in “ Springer eBooks ”
    Joseph L. Pace
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    TLDR Polycystic Ovary Syndrome (PCOS) often leads to severe acne, and lifestyle changes and hormonal treatments can help manage it.
    Nine years ago, the document "The Polycystic Ovary Syndrome and Acne" by Joseph L. Pace explored the link between Polycystic Ovary Syndrome (PCOS) and acne. PCOS, characterized by obesity, amenorrhea, hirsutism, and infertility, often leads to hyperandrogenism, a condition where the body produces excessive androgens, which is crucial to acne development. Dermatologic manifestations of PCOS include hirsutism, acne, acanthosis nigricans, and androgenic alopecia. Persistent, severe, or late-onset acne in women is highly suggestive of PCOS. The pathogenesis of PCOS involves androgens and increased insulin resistance. Lifestyle modifications were recommended as the first-line therapy for all obese women with PCOS. Hormonal treatments used for females with acne include anti-androgens or agents designed to decrease the endogenous production of androgens by the ovary or adrenal gland, such as oral contraceptives, low-dose glucocorticoids, or gonadotropin-releasing hormone (GnRH) agonists.
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