13 citations
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August 2016 in “Reproduction” In this study, nandrolone decanoate treatment in rats caused persistent diestrus and altered steroid receptor expression and sex hormones, especially at higher doses, with partial reversibility at lower doses over time.
July 2023 in “Journal of Clinical Medicine” In this study, researchers investigated factors predicting resistance to clomiphene citrate in women with anovulatory PCOS, identifying AMH and SHBG levels as significant indicators, but they found no reliable thresholds for predicting resistance to the standard 50 mg/day dose.
19 citations
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June 2021 in “The world journal of men's health” This review examines the negative effects of anabolic-androgenic steroid use on the male reproductive system, including impaired testosterone production, sperm production issues, and adverse metabolic consequences without reporting new clinical results.
19 citations
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May 2020 in “American journal of men's health” This review discusses androgen therapy in adolescents, detailing current practices and noting the limited use of commercially available testosterone or dihydrotestosterone formulations; no new results are reported.
5 citations
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January 2023 in “Indian Journal of Endocrinology and Metabolism” This consensus document discusses guidelines for gender-affirming hormone therapy in India, offering recommendations based on a review of existing evidence and expert input, without reporting new clinical results.
6 citations
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February 2016 in “Journal of Microencapsulation” This study found that injectable finasteride microspheres provided a sustained drug release with a minimal initial burst in albino rabbits compared to oral suspension.
5 citations
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May 2018 in “Therapeutic advances in drug safety” This review discusses the role of androgen therapy and neurosteroids in cerebrovascular health, highlighting the potential risks and benefits and the importance of pharmacogenetic testing, but reports no new experimental results.
2 citations
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May 2024 in “European Journal of Investigation in Health Psychology and Education” In this study, a high prevalence of anabolic-androgenic steroid use was observed among bodybuilding athletes in Sergipe, Brazil, regardless of their socioeconomic backgrounds, highlighting the need for increased awareness about the associated health risks.
November 2025 in “ACS Applied Materials & Interfaces” This study found that in a mouse model of androgenetic alopecia, topical application of finasteride-loaded Platycladi cacumen-derived nanovesicles improved hair regrowth more effectively than minoxidil.
August 2025 in “International Journal of Molecular Sciences” This study found that sulforaphane-rich broccoli sprout extract significantly accelerated hair regrowth in a mouse model of androgenetic alopecia, suggesting its potential as a safe and effective natural therapy.
February 2025 in “Journal of Nanobiotechnology” This study developed a microneedle system using black phosphorus nanosheets and baicalin for treating androgenetic alopecia, finding it effectively enhanced drug penetration and follicular targeting while showing synergistic efficacy and safety in preclinical tests, including in vivo model efficacy against testosterone-induced hair loss.
In this review, the authors highlight that drugs promoting androgenic activity or inhibiting estrogenic activity may unmask or worsen androgenetic alopecia in genetically predisposed individuals, indicating the need for careful management in clinical settings.
August 2023 in “Journal of Cosmetic Dermatology” This study observed that in a mouse model of androgenetic alopecia, treatments with LTF, 5% minoxidil, and LTF-DPC-EXO significantly promoted hair regeneration compared to the model group, potentially through modulation of the PI3K/AKT signaling pathway.
October 2022 in “Springer eBooks” This review discusses hormonal treatment strategies for both binary and non-binary transgender people, highlighting the need for personalized approaches and the importance of future research on long-term outcomes.
February 2022 in “Programa de Iniciação Científica - PIC/UniCEUB - Relatórios de Pesquisa” This study found that PRP treatment showed better results than injectable minoxidil for reducing hair loss and promoting hair growth, with noticeable effects after the second application.
June 2025 in “International Journal of Clinical Medical Research” Healthcare professionals need better training and systems for drug interaction reporting, injectable vitamin B12 helps tingling, oral helps numbness, probiotics may help ulcerative colitis, and more research is needed on Post-Finasteride Syndrome.
January 2018 in “Our Dermatology Online” This review summarizes the use of injectable dutasteride mesotherapy for androgenic alopecia and reports improved hair growth when combined with other substances, but highlights the need for further studies to establish long-term protocols.
4 citations
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April 2021 in “Journal of Cosmetic Dermatology” Botulinum toxin may help hair loss by increasing blood flow and reducing harmful factors.
This comprehensive review analyzes androgenetic alopecia treatments, discussing the mechanisms, costs, efficacy, and safety of FDA-approved drugs like minoxidil and finasteride, as well as newer non-FDA-approved options that have shown effectiveness across various studies.
13 citations
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November 2006 in “E-journal of Chemistry” This study developed a rapid and sensitive HPLC method for measuring finasteride in bulk and tablet forms, showing high precision and accuracy compared to the official method.
This study found that a significant portion of counterfeit drugs seized among bodybuilders did not match their labels, with many containing undeclared anabolic steroids or other unexpected active ingredients.
June 2025 in “CA A Cancer Journal for Clinicians” Among transgender men, this study reported a case of breast cancer found incidentally after a gender-affirming mastectomy, despite common lower breast cancer risks in this population, highlighting the importance of cancer screening and careful consideration of hormone therapy management in transgender and gender-diverse individuals.
4 citations
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June 2023 in “Frontiers in Aging” This scoping review evaluates the connection between hypoxia and declining sex hormonal signaling in middle-aged individuals, proposing a "middle-aging hypovascularity hypoxia hypothesis" as a potential mechanism influencing age-related diseases, with implications for developing strategies to maintain healthspan.
4 citations
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September 2025 in “Biomolecules” This narrative review discusses the mixed and evolving evidence regarding glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and their influence on erectile dysfunction in men with type 2 diabetes and obesity, highlighting potential benefits and concerns yet to be clarified.
1 citations
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January 2022 in “Faculty reviews” This review discusses recent advances in understanding hair growth mechanisms and reviews current and emerging therapies, but it presents no new clinical results.
January 2016 in “Elsevier eBooks” Finasteride helps hair growth.
July 2021 in “British Journal of Dermatology” Laser treatment for skin conditions VEN and ILVEN is effective and liked by patients.
118 citations
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September 2004 in “Clinics in Dermatology” This review discusses the role of hormones in acne vulgaris and highlights the need for further research on their mechanisms of action; it reports no new clinical results.
1 citations
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January 2020 in “Aesthetic Surgery Journal” Platelet-rich plasma and stem cell therapies are accepted treatments for hair restoration, with specific protocols recommended for best results, but more standardization is needed in stem cell use.
May 2024 in “Brazilian Journal of Hair Health” This study reported the successful development of finasteride-loaded poly(lactic-co-glycolic acid) nanoparticles, with varying encapsulation efficiencies, aiming to enhance drug delivery for hair growth while minimizing side effects, and noted that an in vivo study will follow to assess efficacy.