Determination of Finasteride in Tablets by High Performance Liquid Chromatography
November 2006
in “
E-journal of Chemistry
”
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Studysummary This study developed a rapid and sensitive HPLC method for measuring finasteride in bulk and tablet forms, showing high precision and accuracy compared to the official method. Our plain-language summary of this paper — not a Tressless recommendation.
The paper presents a validated method for determining the amount of finasteride in tablets using high performance liquid chromatography. The method is accurate, precise, and sensitive, with a linear range of 2.0 to 30 µg mL-¹ and limits of detection and quantification of 0.2 and 0.6 µg mL´¹, respectively. The method is useful for monitoring the content uniformity of tablets and injectables, and purity of finasteride raw material.
