Breast Cancer in a Transgender Man
June 2025
in “
CA A Cancer Journal for Clinicians
”
TLDR Transgender men need personalized cancer care and continued testosterone therapy for well-being.
A 52-year-old transgender man was diagnosed with grade 2 invasive ductal carcinoma three months after starting testosterone therapy and undergoing bilateral mastectomy. This case highlights the importance of cancer screening and inclusive care for transgender individuals, emphasizing the need for personalized treatment plans that consider hormone status and gender-affirming care preferences. Despite the lower breast cancer risk in transgender men, the continuation of testosterone therapy during cancer treatment is crucial for psychosocial well-being. The document calls for a multidisciplinary approach to care and prospective studies to evaluate outcomes, advocating for the inclusion of transgender individuals in clinical trials to establish better treatment protocols.
