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Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Certain drugs change freshwater snail shells to a "banana" shape.

Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.

Store Tectona grandis leaf extracts in slightly acidic, light-protected conditions for best stability.

Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

Finasteride negatively affects fish reproduction and gonadal development.

Using 5-alpha-reductase inhibitors, drugs for prostate issues and hair loss, may lead to eye abnormalities in men.

Finasteride exposure harms tadpole reproduction and hormone balance.

Ritlecitinib is safe and well-tolerated for treating alopecia areata in patients aged 12 and older.

Overexpressing thrombospondin-1 in mice skin prevents UVB-induced skin damage.

CCT128930 is a promising new drug that effectively targets and inhibits a cancer-related protein, showing potential for cancer treatment.

Taking 5 alpha reductase inhibitor medication slightly increases the risk of depression, especially as you get older.

Finasteride harms Daphnia magna's reproduction, growth, and metabolism.

Ritlecitinib shows promise as a versatile treatment for various autoimmune and inflammatory diseases.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Tamsulosin for enlarged prostate may increase the risk of severe low blood pressure, especially when starting or restarting the medication.

The document concludes that various findings in rheumatology offer insights into disease severity, treatment responses, and potential risks in medication, with some limitations due to unspecified participant numbers.

Topical Vorinostat shows promise for treating alopecia areata by promoting hair regrowth.

Sunlight exposure improved a patient's skin condition, and there may be a link between a certain disease and skin growths; a leukemia treatment caused changes in hair color and growth.

Dupilumab for eczema may cause hair loss.

Teriflunomide is an effective and generally safe oral treatment for relapsing MS, reducing relapses and slowing disability progression.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.

Group a wide range of chemicals, not just phthalates, for assessing risks to male reproductive health.

Many substances, including chemicals and metals, can cause skin reactions; careful handling and identification of allergens are crucial to prevent dermatitis.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Some blood-thinning medications can increase the risk of bleeding, and certain factors like genetics and other health conditions affect their safety and effectiveness.

Changing neuroactive steroid levels early in life can affect how adult rats respond to alcohol's stimulating effects.