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This study seeks to clarify the terminology and classification of keratoacanthoma and similar squamous cell carcinoma lesions with central keratin-filled craters to aid in accurate differential diagnosis.

This article discusses the classification and characteristics of infundibular squamous cell carcinoma and highlights the ongoing debate about its differentiation from other carcinoma types, reporting no new clinical results.

In this study, CD4+ non-haematopoietic, skin-resident stem cell-like populations were identified in both murine and human epidermis, suggesting they may serve as potential basal cell carcinoma precursors.

In this case study, researchers reported the first instance of keratoacanthoma on the scalp of an elderly patient in Saudi Arabia, highlighting the diagnostic challenge due to its resemblance to squamous cell carcinoma.

This study found that quiescence in hair follicle stem cells acts as a tumor suppression mechanism for cutaneous squamous cell carcinoma, with Pten activity necessary to maintain this state.

This study concluded that erosive pustular dermatosis of the scalp may be a type of spongiotic, pustular superficial folliculitis, sharing similarities with other neutrophilic dermatoses.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

Understanding where cancer cells come from helps create better prevention and treatment methods.

This study found that squamous cell carcinomas from hair follicle stem cells are more prone to epithelial to mesenchymal transition and metastasis than those from interfollicular epidermis, due to distinct chromatin landscapes.

This study demonstrates that YAP and TAZ are essential for initiating basal and squamous cell carcinomas in mice, and suggests targeting these pathways could be beneficial for treating skin cancers.

In this study, PKC ε transgenic mice exposed to ultraviolet radiation showed increased hair follicle stem cell frequency and altered gene expression compared to wild-type mice, suggesting a potential role in skin cancer susceptibility.

This study found that hairless mice with homozygous mutations developed significantly more aggressive basal cell carcinomas and a heightened inflammatory response to UVB exposure compared to their haired littermates.

This review examines the origins and mechanisms of tumor initiation in common skin cancers, but does not present new experimental findings; it emphasizes the need for further research on cancer stem cells.

This study found that HPV8-induced actinic keratoses may mechanistically involve Lrig1+ hair follicle keratinocyte stem cells, with the E6 gene promoting downstream STAT3 activity in a mouse model.

This paper reviews hidradenitis suppurativa, comparing its clinical and histopathological characteristics to acne, questioning the proposed link to terminal hair follicles, and reports no new results.

This study suggests that both men and women with higher body hair density may have an increased risk of developing basal cell carcinoma and squamous cell carcinoma.

In this case report, a 76-year-old male had an eyelid lesion that mimicked squamous cell carcinoma but was diagnosed as benign inverted follicular keratosis after surgical excision, underscoring the importance of distinguishing between the two for proper management.

The researchers reported that in mice, the type of tumor suppressor deleted along with oncogenic Kras activation in HFSCs influenced the specific squamous cell carcinoma phenotype that developed.

This study found that the enzyme Acer1 plays a crucial role in skin health and tumor prevention by regulating ceramide metabolism in mice.

This report explores the potential cellular origins of keratoacanthoma lesions on the oral mucosa, noting that it reports no new results.

This study by Flores and colleagues found that the type of tumor that develops in a specific subset of epidermal stem cells is influenced by which tumor suppressor gene is deleted.

This paper discusses the role of Runx1 in epithelial biology and pathology, highlighting its dual function as a tumor promoter and suppressor in different contexts, and reports no new experimental findings.

This study found that keratoacanthoma of the lip likely arises from outer root sheath cells, based on the presence of specific keratin markers and periodic acid-Schiff staining patterns.

This study found that epidermal-specific deletion of integrin α3β1 significantly reduces papilloma formation in a skin carcinogenesis model by modulating HB stem cell behavior and CCN2 expression.

This review outlines the clinical and histopathological features that aid in classifying tumors arising from the folliculosebaceous apparatus and reports no new research results.

This study concluded that the Wnt signaling pathway does not significantly influence human keratoacanthoma development, but the overexpression of Sox9 suggests alternate signaling involvement.

This review discusses the identification and roles of different epidermal stem cell types in skin homeostasis and repair, and reports no new experimental findings.

This review discusses recent findings on molecular changes in cutaneous adnexal tumours and reports novel markers and pathways involved, highlighting the diverse oncogenic drivers and tumour suppressor alterations.

This review discusses the reuse of molecular mechanisms involved in embryonic skin development for maintaining adult epidermal homeostasis and reports no new results.

This article discusses the role of stratum corneum disruption in dandruff and suggests that treatments improving scalp barrier integrity along with antifungal activity may be beneficial; it reports no new research findings.