TLDR Keratoacanthomas on lips may originate differently than those on skin.
The document discussed keratoacanthoma (KA), a benign epithelial tumor that typically appears on sun-exposed skin and resembles a low-grade squamous cell carcinoma. It highlighted the role of actinic rays in its development and noted that KAs usually originate from hair follicles. However, the report focused on cases where KAs occur on mucous membranes, such as the lip, where hair follicles are absent. The study aimed to identify the cells responsible for initiating KAs in these unusual locations, suggesting a different histogenesis for mucosal KAs compared to those on skin.
16 citations
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October 2014 in “Oral surgery, oral medicine, oral pathology and oral radiology” Keratoacanthoma comes from hair follicle cells.
February 2024 in “ACS applied bio materials” Keratin microspheres might help hair grow.
50 citations
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July 2008 in “British Journal of Dermatology” 138 citations
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March 2007 in “Experimental cell research” Only a few hair-specific keratins are linked to inherited hair disorders.
276 citations
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January 2005 in “International review of cytology” More research is needed to understand how hair keratins work and their role in hair disorders.
199 citations
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January 2004 in “The International Journal of Developmental Biology” Hair follicle growth and development are controlled by specific genes and molecular signals.
29 citations
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April 2003 in “Experimental dermatology” Human hair follicles grown in vitro maintain normal keratin patterns and structure.
2 citations
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March 1994 in “Oncology Reports” Keratoacanthomas and squamous cell carcinomas have similar keratin patterns, making them hard to tell apart.
