research Pharmacological Treatment of Alopecia
Only minoxidil and finasteride are FDA-approved for hair loss, with other treatments available but less effective or with side effects.
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research Why Do Promising Therapies Stall in Development and How Can We Move Them Forward?
Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.
research Overlap Between Ulerythema Ophryogenes and Keratosis Follicularis Spinulosa Decalvans: A Case Report
A 19-year-old male had two rare skin conditions causing scarring and permanent hair loss.
research Evaluation of Metabolic and Hormonal Parameters in Women with PCOS Living in the Black Sea Region
Women with PCOS have a higher risk of metabolic syndrome and need lifestyle changes and treatment.
research Systemic Lupus Erythematosus and Diabetes Mellitus: Single or Two Entities?
SLE and DM can coexist but are rare and need careful evaluation.
research Lucio Phenomenon Mimicking Vasculonecrotic Erythema Nodosum Leprosum: A Case Report
A man with severe leprosy developed painless ulcers and numbness, treated successfully with multiple drugs and vitamins.
research SnapshotDx Quiz: April 2019
Seborrheic dermatitis is influenced by diet, genetics, and psychological factors.
research Treatment Trial of Mangy One-Humped Camels (Camelus Dromedarius) by Aloe Vera Gel Leaves
Aloe vera gel effectively treated mange in camels.
research Understanding the Role of Propionibacterium Acnes in Acne Vulgaris: The Critical Importance of Skin Sampling Methodologies
Precise skin sampling is crucial to understand the role of P. acnes in acne.
research Role of ACE2 Polymorphism in COVID-19: Impact of Age
Different ACE2 gene versions may affect COVID-19 impact based on age and suggest some hair loss drugs could be potential treatments.
research Advances in Molecular Pathogenesis of Hidradenitis Suppurativa: Dysregulated Keratins and ECM Signaling
Recent findings suggest that genetic factors, immune system issues, and skin cell defects might contribute to the development of hidradenitis suppurativa.
research Application of Multi-Omics Techniques to Androgenetic Alopecia: Current Status and Perspectives
Multi-omics techniques help understand the molecular causes of androgenetic alopecia.
research Notes from the Editor Emeritus
Scalp tools, tracking progress, targeting scalp inflammation, and avoiding certain hair treatments can improve female hair loss treatment.
research Frontal Fibrosing Alopecia: A Decade of Insights
The document says doctors should identify and treat Frontal fibrosing alopecia medically before considering surgery, as treatments often don't work well.
research Trichophyton Mentagrophytes Mimicking Scarring Alopecia
Tinea can cause scarring alopecia in children, and fungal culture is crucial for diagnosis.
research The Microbiome in Patients with Atopic Dermatitis
People with atopic dermatitis have different skin bacteria, and targeting these bacteria might help treat the condition.
research Cannabinoid Signaling in the Skin: Therapeutic Potential of the Cutaneous Cannabinoid System
Cannabinoids may help treat various skin conditions.
research Bipolar Patients and Bullous Pemphigoid After Risperidone Long-Acting Injectable: A Case Report and Literature Review
Long-term use of Risperidone may be linked to a serious skin condition in bipolar patients, affecting their overall well-being.
research Cell-Free DNA Is Elevated in the Serum of Patients with Hidradenitis Suppurativa
Patients with hidradenitis suppurativa have higher levels of cell-free DNA in their blood.
research Bioinspired Engineering of ADSC Nanovesicles in Thermosensitive Hydrogel to Enhance Autophagy of Dermal Papilla Cells for Androgenetic Alopecia Treatment
New treatment using engineered nanovesicles in hydrogel improves hair growth by repairing hair follicle cells in a mouse model of hair loss.
research The Association of Serum Adipokines, Insulin Resistance and Vitamin D Status in Male Patients with Androgenetic Alopecia
Higher leptin and lower vitamin D levels may contribute to male pattern baldness.
research Pharmacologic Interventions in Aging Hair
Minoxidil and Finasteride are effective for male baldness; more research is needed for hair aging treatments.
research Frontal Fibrosing Alopecia: An Update on the Hypothesis of Pathogenesis and Treatment
The document concluded that more research is needed to find the best treatment for Frontal fibrosing alopecia.
research Clinical and Histological Challenge in the Differential Diagnosis of Diffuse Alopecia: Female Androgenetic Alopecia, Telogen Effluvium, and Alopecia Areata – Part II
Diagnosing diffuse alopecia, a hair loss condition, can be challenging and may require a scalp biopsy or tracking the disease's progression when symptoms and skin tests aren't enough.
research New Developments in the Molecular Treatment of Ichthyosis: Review of the Literature
New treatments for ichthyosis, like protein replacement and gene therapy, show promise and may become standard care.
research The Transient Role of Calcium and Vitamin D During the Developmental Hair Follicle Cycle
Vitamin D and calcium are essential for normal hair growth.
research Off-Label Uses of Retinoids in Dermatology
Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.
research Regenerative Biotechnologies in Plastic Surgery: A Multicentric, Retrospective, Case-Series Study on the Use of Microneedling with Low-Level Light/Laser Therapy as a Hair Growth Boost in Patients Affected by Androgenetic Alopecia
Micro-needling with low-level light therapy effectively increases hair growth in people with mild to moderate hair loss.
research First Symposium of Ichthyosis Experts
Experts met to improve care for ichthyosis patients in Spain.
research Disturbance of Immune Microenvironment in Androgenetic Alopecia Through Spatial Transcriptomics
Androgenetic alopecia involves immune cell disruptions, especially increased CD4+ T cells around hair follicles.