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Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.

Superoxide dismutase (SOD) can prevent hair graying in mice.

Primary cilia affect the size and oil production of eye glands but not the oil's makeup.

Substance P may worsen acne by increasing inflammation, but corticosteroids might help by reducing this effect.

Budesonide and N-acetylcysteine reduced tumors and alopecia in mice, regardless of FHIT gene status.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

Enzymes involved in Vitamin A metabolism affect hair growth and type in mice.

The protein Gnαs is found more in black mice than white mice and may influence their coat color.

Hair growth can be induced by certain cells found at the base of hair follicles, and these cells may also influence hair development and regeneration.

New techniques have enhanced our understanding of how stem cells function and the role of mutations in aging tissues, which may influence future cancer therapies.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

A 17-year-old female with adrenogenital syndrome produces very high levels of androgens, which prevent complete feminization despite high estrogen doses.

The document concludes that hair biology is complex and there are still unanswered questions about hair loss and follicle changes.

Androgens reduce BMP2, which weakens the ability of certain cells to help hair stem cells become different types of cells.

Laser hair removal effectiveness depends on targeting hair structures without harming the skin, and improvements require more research and expert collaboration.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Aromatase gene variation may increase female hair loss risk.

The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.

Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.

Growing hair cells with dermal cells can potentially treat hair loss.

Ptprq has multiple forms that change during inner ear development.

Hdac1 and Hdac2 help maintain and protect the cells that control hair growth.

Pangolins have lost some skin-related genes, but kept others, leading to their unique scales and skin features.

Pangolins have lost some skin-related genes, but kept others, showing complex skin evolution.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

The document explains how male reproductive hormones work and affect the body.

Hormones significantly affect women's sexual function, and more research is needed to improve treatments for sexual dysfunction with minimal side effects.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

Different body areas in mice produce different hair types due to interactions between skin layers.