research Paracrine Secreted Frizzled-Related Protein 4 Inhibits Melanocyte Differentiation in Hair Follicle
A protein called sFRP4 from skin cells stops the development of pigment-producing cells in hair.
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research Mapping Penetration of Cosmetic Compounds into Hair Fibers Using Time-of-Flight Secondary Ion Mass Spectrometry (TOF-SIMS)
Different oils penetrate hair differently; monounsaturated oils like olive oil penetrate better than polyunsaturated oils.
research Mesenchymal Stem Cells From Mouse Hair Follicles Reduce Hypertrophic Scarring in a Murine Wound Healing Model
Mouse stem cells from hair follicles can improve wound healing and reduce scarring.
research Role of Allopregnanolone Biosynthesis in Acute Stress-Induced Anxiety-Like Behaviors in Mice
Blocking allopregnanolone production in mice makes them more anxious after stress, but this can be reversed with a drug that mimics allopregnanolone.
research A Connection Between the Mitochondrial Permeability Transition Pore, Autophagy, and Cerebral Amyloidogenesis
Dutasteride may help reduce brain plaque linked to Alzheimer's by affecting cell energy structures and waste removal.
research Valproate, Acetylcarnitine, Folic Acid, and Vitamin B12 in Spinal Muscular Atrophy: Preliminary Data of an Open-Label Study in Children
The treatment with valproate, acetylcarnitine, folic acid, and vitamin B12 may improve muscle strength in children with SMA without significant side effects.
research Udenafil Induces the Hair Growth Effect of Adipose-Derived Stem Cells
Udenafil may help hair grow by activating certain stem cells.
research Chromolaena Odorata Layered-Nitrile Rubber Polymer Transdermal Patch Enhanced Wound Healing In Vivo
The Chromolaena odorata patch significantly speeds up wound healing.
research Regulation of Hair Follicle Development by Exosomes Derived from Dermal Papilla Cells
Exosomes from dermal papilla cells can help grow hair and might treat hair loss.
research Defining the Transcriptional Signature of Esophageal-to-Skin Lineage Conversion
Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.
research An Overview of Alopecia Areata: Etiopathogenesis, Diagnosis, and Management
Alopecia areata is a hair loss condition caused by immune factors and can be treated with JAK inhibitors.
research A Patient With Combined Polycystic Ovary Syndrome And Autoimmune Polyglandular Syndrome Type 2
A woman was the first known case to have both polycystic ovary syndrome and autoimmune polyglandular syndrome type 2, suggesting a need to check for both conditions in similar patients.
research Synergistic Antibacterial Activity and Wound Healing Properties of Selenium-Chitosan-Mupirocin Nanohybrid System: An In Vivo Study on Rat Diabetic Staphylococcus Aureus Wound Infection Model
The nanohybrid system significantly improved wound healing and showed strong antibacterial activity.
research The Interplay of Oxidative Stress and Immune Dysfunction in Hashimoto’s Thyroiditis and Polycystic Ovary Syndrome: A Comprehensive Review
Oxidative stress and immune dysfunction are linked to both Hashimoto's thyroiditis and polycystic ovary syndrome, with diet and specific treatments important for managing these conditions.
research Targeting Superficial or Nodular Basal Cell Carcinoma with Topically Formulated Small Molecule Inhibitor of Smoothened
The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.
research Topical Effect of a Specific Spot-On Treatment Made of Natural Ingredients in Rabbits with Skin Problems: A Pilot Study
The natural topical treatment improved rabbits' skin and hair condition.
research Successful Treatment of Sebaceous Adenitis in a Rabbit with Ciclosporin and Triglycerides
A rabbit with sebaceous adenitis was effectively treated with ciclosporin and medium-chain triglycerides.
research Hair Growth Promotion Effect of Cedrol Cream and Its Dermatopharmacokinetics
Cedrol cream is more effective and safe for promoting hair growth than traditional treatments.
research In Silico Analysis of the Age-Dependent Evolution of the Transcriptome of Mouse Skin Stem Cells
The research found that the gene activity in mouse skin stem cells changes significantly as they age.
research Encapsulation of Curcumin in Polystyrene-Based Nanoparticles: Drug Loading Capacity and Cytotoxicity
Curcumin can be effectively loaded into polystyrene nanoparticles, which are safe for human cells and more biocompatible with curcumin inside.
research New Biomarkers to Evaluate Hyperandrogenemic Women and Hypogonadal Men
The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.
research Ovarian SAHA Syndrome Is Associated With a More Insulin-Resistant Profile and Represents an Independent Risk Factor for Glucose Abnormalities in Women With Polycystic Ovary Syndrome: A Prospective Controlled Study
Ovarian SAHA syndrome makes women with PCOS more resistant to insulin and increases their risk of blood sugar problems.
research Ultrasound-Activated Particles as CRISPR/Cas9 Delivery System for Androgenic Alopecia Therapy
Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.
research Indirect Clinical Markers for the Detection of Anabolic Steroid Abuse Beyond Conventional Doping Control in Athletes
New signs like changes in blood markers, physical symptoms, and behavioral shifts may help detect hidden steroid use in athletes.
research Does Myo-Inositol Oxygenase, the Only Enzyme to Catalyze Myo-Inositol In Vivo, Play a Role in the Etiology of Polycystic Ovarian Syndrome?
The enzyme myo-inositol oxygenase is not linked to the cause of polycystic ovarian syndrome.
research Advances in Cosmetic Dermatology
The book provides an overview of new trends and techniques in cosmetic dermatology.
research News in Brief
Researchers discovered potential origins and new treatments for skin cancer, including biomarkers for melanoma and therapies that reduce tumor growth.
research Induction of Vascular Endothelial Growth Factor Messenger Ribonucleic Acid Expression in Stored Micrografts by Aminoguanidine
Aminoguanidine increases a specific growth signal in stored hair grafts, which may help them survive better after being transplanted.
research Platelet-Rich Plasma for Hair Loss
Platelet-Rich Plasma (PRP), a protein-rich extract from a patient's blood, shows promise in improving hair density, thickness, and quality, but the best method of use and number of treatments needed for noticeable results are still unclear.
research Lack of Association Between Clinical and Biochemical Hyperandrogenism in Patients With Polycystic Ovary Syndrome
Clinical signs of excess male hormones and actual hormone levels in the blood do not always match in women with polycystic ovary syndrome.